微波、射频及激光在离体猪甲状腺消融实验的对比研究

发布时间：2018-06-01 00:05

  本文选题：甲状腺 + 消融技术　； 参考：《中国普通外科杂志》2016年05期

【摘要】：目的:在离体猪甲状腺组织上比较微波消融(MWA)、射频消融(RFA)、激光消融(LA)的消融特性和温度变化,为临床制定消融方案提供参考。方法:将150个新鲜离体猪甲状腺均分为3组,分别行MWA(20 W 5 min)、RFA(5 W)、LA(3 W 1200 J),各组消融同时在靶心处进行实时测温和超声观察,消融结束后沿针道剖开,观察消融灶形态,计算消融灶体积并进行病理学检查。结果:3组间比较,MWA组消融体积最大(1 597.09 mm~3),LA组次之(780.89 mm~3),RFA组最小(162.20 mm~3),差异均有统计学意义(均P0.05)。MWA及RFA温升曲线陡直,而LA温升曲线平缓,但最高温度最高(200.9℃)。RFA组消融区域组织分布均匀,未见到明显的炭化和气化空腔;MWA组消融区域可见碳化,但无明显气化空腔;LA组消融灶中央可见碳化与气化空腔。消融灶由内向外,RFA组为凝固坏死区、充血反应区;MWA组为炭化区、凝固坏死区及充血反应区;LA组为气化空腔区、炭化区、凝固坏死区及充血反应区。结论:MWA、RFA及LA的消融范围、温升曲线及消融区病理变化存在差异,了解各自的消融特点有利于3种消融技术的合理应用。
[Abstract]:Objective: to compare the characteristics and temperature changes of microwave ablation (MWA), radiofrequency ablation (RFAA) and laser ablation (LAA) in pig thyroid tissue in vitro. Methods: 150 fresh isolated pig thyroid glands were divided into 3 groups. MWA(20 W 5 min and RFAA 5 WCA 3 W 1200 J / L were performed respectively. The ablation was performed simultaneously in the target site with real-time temperature measurement and ultrasound observation. After ablation, the ablation focus was dissected along the needle canal to observe the morphology of the ablation focus. The volume of ablation was calculated and pathological examination was performed. Results the largest ablation volume (1 597.09 mm) in the P0.05).MWA group was higher than that in the LA group (780.89 mm). The difference was statistically significant (all the P0.05).MWA and RFA temperature rise curves were steeper than those in the LA group). However, the highest temperature was 200.9 鈩，

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