有氧运动和抗阻运动对糖调节受损患者空腹血糖及胰岛素抵抗的影响研究

发布时间：2018-06-08 16:38

本文选题：糖尿病前期 + 有氧运动　；参考：《中国全科医学》2017年29期

【摘要】：目的探讨有氧运动和抗阻运动对糖调节受损(IGR)患者空腹血糖(FPG)和胰岛素抵抗的干预效果,为有效预防和延缓糖尿病前期进展为糖尿病提供依据。方法于2015年6—8月在桂林市叠彩、南门及秀峰社区卫生服务中心长期管理的居民中筛选IGR患者143例,采用随机数字表法分为对照组(47例)、有氧组(48例)、抗阻组(48例)。对照组每3个月随访1次,但不对其进行行为干预。有氧组进行中等强度的有氧运动,主要为韵律操、有氧健身操等。抗阻组进行中等强度的抗阻运动,采用弹力绳以60%~70%的单次最大负荷完成指定动作,主要选取腰背部及腹部肌群、腿部及臀部肌群、上肢肌群进行训练。有氧组和抗阻组总运动时间均为50 min/次,隔日1次。分别于干预前及干预3、6、12个月时检测FPG、空腹胰岛素(FINS)水平,计算胰岛素抵抗指数(HOMA-IR)、胰岛素作用指数(IAI)。结果干预结束后,对照组38例、有氧组39例、抗阻组38例完成本研究。时间与运动方式对FPG、FINS、HOMA-IR、IAI的交互作用显著,时间、运动方式对FPG、FINS、HOMA-IR、IAI的主效应显著(P0.05)。干预3个月时,有氧组、抗阻组FPG低于对照组;干预6个月时,有氧组、抗阻组FPG、FINS、HOMA-IR低于对照组,IAI高于对照组,抗阻组FPG低于有氧组;干预12个月时,有氧组、抗阻组FPG、FINS、HOMA-IR低于对照组,IAI高于对照组(P0.05)。干预3个月时,有氧组、抗阻组FPG、HOMA-IR低于干预前,IAI高于干预前;干预6个月时,有氧组、抗阻组FPG、FINS、HOMA-IR低于干预前,IAI高于干预前;干预12个月时,有氧组、抗阻组FPG低于干预前,对照组、有氧组、抗阻组FINS、HOMA-IR低于干预前,IAI高于干预前(P0.05)。结论有氧运动和抗阻运动对IGR患者的FPG、FINS、胰岛素抵抗、胰岛素敏感性均有明显的改善作用,效果相似。
[Abstract]:Objective to investigate the effects of aerobic exercise and resistance exercise on fasting blood glucose (FPG) and insulin resistance in patients with impaired glucose regulation (IGR), so as to provide evidence for preventing and delaying the advance of diabetes mellitus. Methods 143 IGR patients were selected from the residents in Guilin City from June to August 2015. The IGR patients were randomly divided into control group (n = 47), aerobic group (n = 48) and resistance group (n = 48). The control group was followed-up once every 3 months, but did not intervene in their behavior. The aerobic group carries on the moderate intensity aerobic exercise, mainly for the rhythm exercise, the aerobic aerobics and so on. In the resistance group, the middle strength resistance exercise was carried out, and the designated action was completed by using elastic rope with a single maximum load of 60% and 70%, mainly selecting the waist, back and abdomen muscles, the leg and hip muscles, and the upper limb muscle group for training. The total exercise time of aerobic group and resistance group was 50 min/ once every other day. The levels of FPG, fasting insulin and fins were measured before intervention and at 6 and 12 months after intervention respectively. The insulin resistance index (HOMA-IRN) and insulin action index (IIA) were calculated. Results after the intervention, 38 cases in the control group, 39 cases in the aerobic group and 38 cases in the resistance group completed the study. The interaction between time and exercise mode on FPGN FINSH-IRMA-IRIAI was significant, and time and exercise mode had significant effect on FPGG FINSH-IRMA-IRI IAI (P0.05). At 3 months of intervention, FPG in the aerobic group was lower than that in the control group, and at 6 months after intervention, the FPG of the aerobic group was lower than that of the control group, and the FPG of the resistance group was lower than that of the aerobic group. At 12 months after intervention, the FPG in the aerobic group was lower than that in the control group, and at 12 months after intervention, the FPG of the resistance group was lower than that of the aerobic group. HOMA-IR in resistance group was lower than that in control group (P 0.05). In aerobic group, HOMA-IR of resistance group was lower than that before intervention, and at 6 months after intervention, the level of FINSHOMA-IR in aerobic group was lower than that before intervention. At 12 months after intervention, FPG in aerobic group was lower than that before intervention. FINSHOMA-IR in control group, aerobic group and resistance group was lower than that before intervention (P 0.05). Conclusion aerobic exercise and resistance exercise can significantly improve FPGG FINS, insulin resistance and insulin sensitivity in IGR patients, and the effects are similar.
【作者单位】：广西医科大学第一附属医院内科;广西中医药大学第一附属医院护理部;广西医科大学护理学院科教科;
【基金】：广西医疗卫生适宜技术研究与开发课题项目(S201413-03) 广西研究生教育创新计划项目(YCSZ2015111)
【分类号】：R587.1

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