雷珠单抗辅助双微创眼前后节联合手术治疗合并白内障的增殖性糖尿病视网膜病变

发布时间：2018-06-15 01:49

本文选题：雷珠单抗 + 微切口超声乳化术　；参考：《中国现代医学杂志》2017年28期

【摘要】：目的分析雷珠单抗辅助双微创眼前后节联合手术在白内障合并增殖性糖尿病视网膜病变中的治疗优势。方法收集行雷珠单抗辅助微切口白内障超声乳化联合23G玻璃体切割术的33例患者33眼,观察术后视力改善情况及术中、术后早期、远期并发症,随访1~24个月。结果 33例手术均顺利完成,术中均无角膜切口渗漏、前房消失及后囊膜破裂发生,术中处理增殖膜时视网膜出血2例(6.1%),无医源性视网膜裂孔发生。术后视力较术前改善29例(87.9%),视力不变4例(12.1%)。末次随访时手术切口均愈合良好,前房中深,晶状体缺如或人工晶体在位,无人工晶体夹持及移位发生,后囊膜混浊5例(15.2%),继发新生血管性青光眼1例(3.0%),玻璃体腔积血2例(6.1%)。结论雷珠单抗辅助双微创眼前后节联合手术很大程度地减小了手术创伤,角膜切口无需缝合即可获得良好的密闭性,且雷珠单抗减少术中视网膜出血、易化增殖膜剥除,治疗合并白内障的增殖性糖尿病视网膜病变具有显著优势且安全可靠。
[Abstract]:Objective to evaluate the therapeutic advantages of combined surgery of double minimally invasive posterior anterior ganglion combined with Lei Zhu McAb in the treatment of cataract with proliferative diabetic retinopathy (proliferative diabetic retinopathy). Methods 33 eyes of 33 patients with cataract treated by phacoemulsification combined with 23 G vitrectomy were collected. The postoperative visual acuity, early postoperative complications and long-term complications were observed and followed up for 1 ~ 24 months. Results all the 33 cases were successfully completed. There were no corneal incision leakage, anterior chamber disappearance and posterior capsule rupture. There were 2 cases of retinal hemorrhage during the treatment of proliferative membrane, and no iatrogenic retinal rupture occurred. The postoperative visual acuity was improved in 29 cases (87.9%), and the visual acuity was unchanged in 4 cases (12.1%). At the last follow-up, the incision healed well, deep anterior chamber, absence of intraocular lens or intraocular lens in position, no intraocular lens clamping and displacement, posterior capsule opacification in 5 cases, secondary angiogenic glaucoma in 1 case, vitreous hemorrhage in 2 cases, and intraocular lens hemorrhage in 2 cases. Conclusion the combined operation of combined double minimally invasive posterior segment surgery with Lei Zhu McAb can greatly reduce the surgical trauma, and the corneal incision can obtain good closure without suture, and it can reduce the retinal hemorrhage and facilitate the exfoliation of proliferative membrane. The treatment of proliferative diabetic retinopathy with cataract has significant advantages and is safe and reliable.
【作者单位】：郑州大学第二附属医院眼科;
【分类号】：R587.2;R779.6

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