2型糖尿病患者尿路感染病原菌分布与耐药性及相关因素分析

发布时间：2018-06-16 23:39

本文选题：型糖尿病 + 尿路感染　；参考：《中华医院感染学杂志》2017年15期

【摘要】：目的分析2型糖尿病(T2DM)合并尿路感染的病原菌分布、耐药性及相关因素,为感染预防和控制工作提供参考依据。方法选取2014年6月-2016年10月医院收治的T2DM患者502例作为研究对象,对患者尿路感染的发生率及相关因素进行观察和分析;对感染患者病原菌分布及耐药性进行检测。结果有126例患者发生尿路感染,感染率为25.1%;共分离出131株病原菌,以革兰阴性菌为主,共104株占79.4%;革兰阴性菌对氨苄西林、环丙沙星等药物的耐药率较高,未检出对亚胺培南耐药的菌株;logistic多元回归分析结果显示,患者年龄、住院天数、联合应用抗菌药物情况、入院空腹血糖水平、入院糖化血红蛋白水平、糖尿病病程是发生T2DM合并尿路感染的独立危险因素(P0.05)。结论 T2DM患者合并尿路感染的病原菌分布、耐药性和相关因素具有一定的特点,临床医务人员应给予密切的监控和有效的干预,以达到提高感染防治效率、改善患者预后的目的。
[Abstract]:Objective to analyze the distribution of pathogenic bacteria, drug resistance and related factors in type 2 diabetes mellitus (T2DM) complicated with urinary tract infection, so as to provide reference for the prevention and control of infection. Methods 502 patients with T2DM from June 2014 to October 2016 were selected as the study subjects, the incidence and related factors of urinary tract infection were observed and analyzed, and the distribution of pathogenic bacteria and drug resistance were detected. Results there were 126 patients with urinary tract infection, the infection rate was 25.1.The results showed that 131 pathogenic bacteria were isolated, 104 of them were Gram-negative bacteria (79.4%), and Gram-negative bacteria were resistant to ampicillin and ciprofloxacin. Logistic multiple regression analysis showed that the patients' age, hospitalization days, combined use of antimicrobial agents, fasting blood glucose level and glycosylated hemoglobin level in hospital were determined by logistic regression analysis. The course of diabetes is an independent risk factor for T2DM complicated with urinary tract infection (P0.05). Conclusion the distribution of pathogens, drug resistance and related factors in patients with T2DM complicated with urinary tract infection have some characteristics. Clinical medical staff should give close monitoring and effective intervention to improve the efficiency of infection prevention and treatment. Objective to improve the prognosis of patients.
【作者单位】：天津医科大学代谢病医院内分泌研究所;山西医科大学第一医院泌尿外科;
【分类号】：R587.2

【参考文献】