慢性酒精中毒患者血清和肽素的测定及其临床意义

发布时间：2018-06-21 13:52

  本文选题：慢性酒精中毒 + 和肽素　； 参考：《延边大学》2015年硕士论文

【摘要】：目的探讨慢性酒精中毒患者血清和肽素水平及其与空腹血糖、胆固醇、甘油三酯、LDL-C、HDL-C的相关性,进一步探讨应激标志物和肽素在判断慢性酒精中毒患者中的临床意义。方法慢性酒精中毒患者41例,按不同饮酒年限分为饮酒20年以下组、饮酒20年以上组,按头部CT诊断分为CT正常组、CT异常组；正常对照组20例。采用双抗体夹心法测定血清和肽素水平,同时测定空腹血糖、胆固醇、甘油三酯、LDL-C、HDL-C水平,并分析它们之间的关系。结果1.慢性酒精中毒患者血清和肽素(47.92±7.12pg/ml)低于正常对照组(57.39±6.59pg/ml),有显著性差异(P0.01)。2.慢性酒精中毒患者饮酒20年组血清和肽素(47.13±7.94pg/ml)与饮酒≥20年组(48.48±6.59pg/ml)之间无显著性差异(P0.05)。3.慢性酒精中毒患者CT异常组血清和肽素(50.41±6.17pg/ml)略高于CT正常组(46.78±7.11pg/ml),但无显著性差异(P0.05)。4.慢性酒精中毒患者血清和肽素与空腹血糖、胆固醇、甘油三酯、LDL-C及HDL-C没有显著的相关性(P0.05)。结论1.慢性酒精中毒患者血清和肽素水平降低,可能对慢性酒精中毒有临床意义。2.随着饮酒年限的增加未发现血清和肽素随之降低的规律性。3.慢性酒精中毒患者血清和肽素对评价是否合并脑血管病无辅助意义。
[Abstract]:Objective to investigate the relationship between serum and peptide levels in patients with chronic alcoholism and their correlation with fasting blood glucose, cholesterol and LDL-Con HDL-C, and to explore the clinical significance of stress markers and peptides in judging chronic alcoholism. Methods Forty-one patients with chronic alcoholism were divided into two groups according to different drinking years: 20 cases of normal group, 20 cases of normal group and 20 cases of normal group according to CT diagnosis. Serum and peptide levels were measured by double antibody sandwich method, fasting blood glucose, cholesterol, LDL-Con HDL-C were measured and the relationship between them was analyzed. Result 1. The levels of serum and peptide in patients with chronic alcoholism were 47.92 卤7.12pg / ml and 57.39 卤6.59pg / ml, respectively. There was no significant difference in serum and peptide levels between 20 years drinking group (47.13 卤7.94 PG / ml) and drinking 鈮，

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