尿液及血清中碘、BPA水平与甲状腺肿发病率的相关性研究

发布时间：2018-06-22 21:14

  本文选题：甲状腺肿 + 尿液　； 参考：《中国地方病防治杂志》2016年04期

【摘要】：目的分析研究甲状腺肿患者尿液及血清中碘、双酚A(BPA)水平与正常者之间的差异,以期为甲状腺肿的预防提供新的思路。方法 62例甲状腺肿患者作为甲状腺肿组,另选取同期在本院体检健康者62例作为正常组,对其血清及尿液进行检测,对比两组研究对象尿碘、尿BPA及血清碘和BPA水平。结果甲状腺肿组尿碘、尿碘/肌酐水平均明显高于正常组,差异有统计学意义(P0.05);甲状腺肿组尿BPA、尿BPA/肌酐水平均明显高于正常组,差异有统计学意义(P0.05);甲状腺肿组血清碘和BPA水平与正常组比较差异无统计学意义(P0.05)。结论高尿碘状态、高尿BPA水平与甲状腺肿发病密切相关,并且尿液中的BPA和碘之间呈正相关。
[Abstract]:Objective to study the difference of iodine, bisphenol A (BPA) levels in urine and serum between patients with goiter and normal patients, so as to provide a new idea for the prevention of goiter. Methods Sixty-two patients with goiter were selected as goiter group and 62 healthy persons in our hospital were selected as normal group. The serum and urine levels of iodine, BPA, serum iodine and BPA were compared between the two groups. Results urinary iodine and urinary iodine / creatinine levels in goiter group were significantly higher than those in normal group (P0.05), urinary BPA and urinary BPA / creatinine levels in goiter group were significantly higher than those in normal group. The serum iodine and BPA levels in goiter group were not significantly different from those in normal group (P0.05). Conclusion hyperiodine status and BPA level are closely related to the incidence of goiter, and there is a positive correlation between BPA and iodine in urine.
【作者单位】： 海南省东方市人民医院内一科;海南省东方市人民医院;海南省东方市人民医院化验科;海南医学院;
【基金】：国家自然科学基金面上项目;基金编号:81372465
【分类号】：R581.3
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本文编号：2054247