2011~2014年邢台市糖尿病患病率变化趋势及危险因素分析

发布时间：2018-06-24 14:25

本文选题：邢台市 + 2型糖尿病　；参考：《河北医科大学》2015年硕士论文

【摘要】：目的:通过对2011年至2014年在邢台市医专第二附属医院参加体检的人群的2型糖尿病(Type 2 Diabetes Mellitus,T2DM)和空腹血糖受损(Impaired Fasting Glucose,IFG)的患病率描述和分析,了解不同年份邢台市的糖尿病患病率变化趋势,进而探讨影响T2DM患病的危险因素,以便为人群的T2DM的防治工作提供科学的依据。方法:将2011~2014年在邢台市医专第二附属医院参加体检的人群作为研究对象,从中选取体检资料比较完整的人群纳入分析对象,研究内容主要包括研究对象的人口统计学特征(姓名、年龄、性别)、体格测量(包括身高、体重和血压)、血液的生化检查(包括空腹血糖水平、血清总胆固醇、甘油三酯等)。对调查对象的T2DM和IFG患病率在2011年至2014年的变化趋势进行描述性分析;同时对影响T2DM和IFG患病率的因素进行单因素logistic回归分析;以是否患糖尿病作为应变量,以年龄、性别、体质指数、高血压、血脂异常等自变量进行多因素的logistic回归分析。结果:1研究对象人口学特征本研究中,2011年调查6541人,其中男性4519人(占69.1%),女性2022人(占30.9%);2012年调查6312人,其中男性4112人(占65.1%),女性2200人(占34.9%);2013年调查8107人,其中男性5535人(占68.3%),女性2572人(占31.7%);2014年调查6394人,其中男性4267人(占66.7%),女性2127人(占33.3%)。2从2011年至2014年,T2DM的标化患病率呈增长趋势(6.09%,6.51%,7.94%,7.72%),差异有统计学意义(χ2=102.39,P0.05)。从2011年至2012年、2013年至2014年T2DM标准化后的患病率变化不大,而2013年T2DM标准化后的患病率与2012年相比,患病率上升了21.97%,提示在2011年至2012年与2013年至2014年2型糖尿病的发病基本没变化,而2012年至2013年2型糖尿病的发病明显增高。3从2011年至2014年,IFG标化患病率随年份增长也呈现整体上升趋势(8.51%,8.55%,10.85%,10.45%),而且差异均有统计学意义(χ2=143.82,P0.05)。IFG标化后患病率与T2DM变化趋势相似,只有在2012年至2013年变化明显,患病率上升了26.90%。4 2011年至2014年不同性别T2DM的患病率及变化趋势。2011年至2014年男性T2DM标化患病率有逐渐增高的趋势(6.62%,7.34%,9.21%,9.56%);而女性T2DM标化患病率随着年份的增长变化不大(4.86%,4.13%,5.85%,4.97%),但呈现上下波动状态。5 2011年至2014年不同性别IFG的患病率及变化趋势。2011年至2014年,男性IFG标化患病率呈增长趋势(9.62%,10.56%,9.58%,12.97%),女性IFG标化患病率随着年份的增长变化的规律性不强(5.88%,4.58%,6.97%,5.58%),呈现波动状态。6在2011年至2014年,每个年份男性T2DM的标化患病率均明显高于女性(6.62%4.86%、7.34%4.13%、9.21%5.85%、9.56%4.97%),而且差异均具有统计学意义(χ2=18.68,59.79,66.01,99.65,P0.05)。2011年,男性的T2DM患病率在51~岁年龄段达到最高值,而女性的T2DM患病率在61~岁年龄段达到高峰,在41~50岁年龄段,男性与女性差异最大,且差异有统计学意义(χ2=24.45,P0.05);在2012、2013和2014年,男性和女性的T2DM患病率均在61~岁年龄段达到最高值,在各个年龄段,男性的T2DM患病率均高于女性,而且在41~50岁年龄段差异最大,差异均有有统计学意义(χ2=15.07,28.63,24.20,P0.05)。7年龄对T2DM患病率的影响:在2011年-2014年,在41~50岁、51~60岁、61~岁年龄段T2DM的患病率均与18~30岁年龄段有差异,差异有统计学意义,而且随年龄组的递增,患T2DM的风险性增大。8超重/肥胖对T2DM的患病率的影响:超重组(24~28)和肥胖组(≥28)相对于正常组,T2DM患病率差异明显,而且有统计学意义;超重和肥胖是T2DM患病的危险因素,肥胖组相对正常组T2DM患病的风险性比超重组相对正常组T2DM患病的风险性要大,而且随着年份的增长,风险性均增大。9高血压、高TC症、高TG症对T2DM患病率的影响:在2011-2014年,高血压者、高TC症者和高TG症者T2DM的患病率与血压正常者、TC正常者和TG正常者的患病率均有差异,差异均有统计学意义,而且高血压、高TC症和高TG症均是T2DM患病的危险因素。10多因素非条件Logistic回归分析的结果表明,2011、2012、2013和2014年,在排除了其他混杂因素后,年龄、超重/肥胖、高血压、高TG症均是T2DM发生的危险因素(OR值1),说明年龄较高者比年龄低者患T2DM的机率大,超重或肥胖者比BMI正常者患T2DM的风险高,血压越高、TG值越高,TC值越高,T2DM患病的危险性就越大。结论:1在2011年至2014年,邢台市成年居民T2DM以及IFG患病率迅速增长。2男性T2DM以及IFG的患病率明显高于女性,而且在近四年间,在不同的年龄段差异明显。3年龄越大、高血压患者、超重和肥胖者、血脂异常者患糖尿病的风险升高。
[Abstract]:Objective: to describe and analyze the prevalence of type 2 diabetes (Type 2 Diabetes Mellitus, T2DM) and impaired fasting blood glucose (Impaired Fasting Glucose, IFG) in the Second Affiliated Hospital of Xingtai medical secondary hospital from 2011 to 2014, to understand the trend of diabetes prevalence in different years in Xingtai and to explore the influence of T2DM. The risk factors of the disease are provided in order to provide scientific basis for the prevention and control of T2DM in the population. Methods: the population of the Second Affiliated Hospital of Xingtai Medical College, 2011~2014, was taken as the research object. Characteristics (name, age, sex), physical measurement (including height, weight and blood pressure), biochemical examination of blood (including fasting blood glucose level, serum total cholesterol, triglyceride, etc.). Descriptive analysis of the prevalence rates of T2DM and IFG in the subjects from 2011 to 2014; and factors affecting the prevalence of T2DM and IFG Single factor Logistic regression analysis, logistic regression analysis was performed on the independent variables of age, sex, body mass index, hypertension, and dyslipidemia. Results: in 1 subjects, 6541 people were investigated in this study in 2011, including 4519 men (69.1%), 2022 women (30.9%); 2012 The annual survey of 6312 people, of which 4112 were male (65.1%) and 2200 women (34.9%), 8107 were investigated in 2013, including 5535 men (68.3%) and 2572 women (31.7%). In 2014, there were 6394 people, among them male 4267 (66.7%) and.2 from 2011 to 2014. The standardized prevalence rate of T2DM was increasing. 7.72%) the difference was statistically significant (x 2=102.39, P0.05). From 2011 to 2012, the prevalence rate of T2DM after the standardization of 2013 to 2014 was not significant, but the prevalence rate of T2DM after 2013 T2DM was higher than that in 2012. From 2 to 2013, the incidence of type 2 diabetes was significantly higher in.3 from 2011 to 2014. The IFG standardized prevalence rate also increased with annual growth (8.51%, 8.55%, 10.85%, 10.45%), and the difference was statistically significant (x 2=143.82, P0.05).IFG standardized prevalence rate was similar to that of T2DM, only from 2012 to 2013. The prevalence rate of 26.90%.4 was increased from 2011 to 2014. The prevalence and changes of T2DM in different sexes were increased from.2011 to 2014 (6.62%, 7.34%, 9.21%, 9.56%), while the prevalence rate of T2DM in women changed little with year's increase (4.86%, 4.13%, 5.85%, 4.97%), but the incidence of T2DM was.5 20. The prevalence and change trend of different sex IFG from 11 to 2014 from.2011 to 2014, the male IFG standardized prevalence rate was increasing (9.62%, 10.56%, 9.58%, 12.97%). The prevalence rate of female IFG standardization was not strong (5.88%, 4.58%, 6.97%, 5.58%) with the year's increase, which showed a fluctuating state.6 from 2011 to 2014, each year male T2 The standardized prevalence rate of DM was significantly higher than that of women (6.62%4.86%, 7.34%4.13%, 9.21%5.85%, 9.56%4.97%), and the difference was statistically significant (x 2=18.68,59.79,66.01,99.65, P0.05).2011 years, and the prevalence rate of male T2DM reached the highest in 51~ age, while the T2DM prevalence rate of women reached the peak in the age segment of the 61~ year. The difference between male and female is the greatest, and the difference is statistically significant (x 2=24.45, P0.05). In 20122013 and 2014, the prevalence rate of T2DM in men and women reached the highest in the age of 61~. In all age groups, the prevalence rate of T2DM in male was higher than that in women, and the difference was the largest in 41~50 age group (x 2=15.). The effect of 07,28.63,24.20, P0.05).7 age on the prevalence of T2DM: in -2014 year 2011, at 41~50 years, 51~60 years, and 61~ years old, the prevalence of T2DM is different from that of 18~30 years old, and the difference is statistically significant, and the risk of T2DM is increased with the increase of age group. The prevalence of T2DM was significantly different in the obese group (> 28) compared with the normal group, and there was a statistically significant difference. Overweight and obesity were risk factors for T2DM disease. The risk of T2DM prevalence in the obese group was higher than that in the normal group compared with the normal group T2DM, and with the growth of the year, the risk increased.9 hypertension and high TC The effect of high TG's disease on the prevalence of T2DM: in 2011-2014 years, the prevalence of T2DM in high blood pressure, high TC and high TG patients is different from those of normal people with normal blood pressure, normal TC and normal TG, and the difference is statistically significant, and hypertension, high TC and high TG are all.10 multifactor non conditional Logisti. The results of C regression analysis showed that age, overweight / obesity, hypertension, and high TG were all risk factors for T2DM (OR value 1) after excluding other confounding factors in 201120122013 and 2014, indicating that older people were more likely to suffer from T2DM than those with older age, and those who were overweight or fat were at higher risk for T2DM than those with normal BMI, the higher the blood pressure, the greater the TG value, the higher the TG value. Higher, the higher the TC value, the greater the risk of T2DM disease. Conclusion: 1 from 2011 to 2014, the prevalence rate of T2DM and IFG in adult residents in Xingtai was rapidly increased, and the prevalence rate of.2 male T2DM and IFG was significantly higher than that of women. And in the last four years, the greater the.3 age in different age groups, the hypertension, overweight and obese, blood lipid difference. The risk of diabetes is higher.
【学位授予单位】：河北医科大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R587.1

【参考文献】