肥胖与环境内分泌干扰物暴露的关系及机制

发布时间：2018-06-27 05:54

本文选题：内分泌干扰物 + 雌激素　；参考：《重庆医学》2017年24期

【摘要】：正肥胖是机体能量失衡导致脂肪过度积聚为重要特征的一种代谢异常,主要表现为脂肪细胞数量异常增加和体积异常增大。世界卫生组织(WHO)认为遗传因素、不合理的饮食和生活方式是导致肥胖的主要病因,肥胖症病由遗传和环境因素共同影响的复杂性疾病,其机制和确切原因并未阐明。环境内分泌干扰物(endocrine disrupting chemicals,EDCs)是指干扰体内稳态调节、繁殖、发育行为及相关激素的合成、分泌、转运、结
[Abstract]:Positive obesity is a metabolic abnormality characterized by excessive accumulation of fat due to energy imbalance, which is mainly characterized by an abnormal increase in the number of adipocytes and an abnormal increase in volume. The World Health Organization (WHO) believes that genetic factors, unreasonable diet and lifestyle are the main causes of obesity, obesity is affected by genetic and environmental factors of the complex diseases, its mechanism and exact reasons have not been clarified. Environmental endocrine disruptor (endocrine disrupting chemicalsEDCs (EDCs) refers to the disturbance of homeostasis, reproduction, developmental behavior and the synthesis, secretion, transport and formation of related hormones in vivo.
【作者单位】：遵义医学院公共卫生学院;
【基金】：国家自然科学基金资助项目(81360439;81560527) 贵州省教育厅青年基金(黔教合KY字[2013]198) 贵州省科技厅遵义医学院联合基金重点项目(黔科合LH[2014]7543) 遵义医学院招标课题(2013F-68;2016F-750);遵义医学院重点学科建设经费(2015) 教育部2016年留学人员基金
【分类号】：R589.2

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