抗阻运动对糖尿病前期伴轻度高血压人群血压的影响

发布时间：2018-06-27 19:56

本文选题：抗阻运动 + 糖尿病前期　；参考：《中国现代医学杂志》2017年28期

【摘要】：目的研究不同运动方式对社区糖尿病前期(IGR)人群血压的控制效果。方法于2015年6~8月在桂林的3个社区卫生服务中心长期管理的社区居民中筛选出符合标准的IGR合并轻度高血压人群83人,随机分为3组,经过1年的干预和随访,最终收集到67人的完整数据:抗阻运动组22人、有氧运动组23人、对照组22人。干预期间,对照组保持原有的生活方式,抗阻和有氧运动组分别进行相应的运动干预,约50 min/次,以集体形式隔天训练。对干预后3、6、12个月抽血查空腹血糖、空腹胰岛素和糖化血红蛋白(HbA1c),测血压,计算胰岛素抵抗指数(HOMA-IR)。结果 (1)不同时间点之间的HbA1c、HOMA-IR、收缩压(SBP)、舒张压(DBP)比较,差异有统计学意义(F=22.415、9.289、32.689和6.713,均P=0.000);3组间的HbA1c、HOMA-IR、SBP、DBP比较,差异有统计学意义(F=16.525、4.241、26.436和4.653,P=0.000、0.044、0.000和0.013),干预后抗阻运动组和有氧运动组的HbA1c、HOMA-IR、SBP、DBP低于对照组;3组的HbA1c、HOMA-IR、SBP、DBP变化趋势差异有统计学意义(F=19.134、4.782、22.520和6.792,均P=0.000),干预期间,对照组各指标总体呈上升趋势,两运动组各指标总体呈下降趋势,虽然两运动组不同时段各指标比较差异无统计学意义(P0.05),但抗阻运动组的HbA1c、HOMAIR的下降幅度大于有氧运动组,且SBP、DBP下降幅度小于有氧运动组。(2)干预3个月时,有氧和抗阻运动组的HbA1c、HOMA-IR、DBP均低于干预前,有氧运动组SBP低于干预前;干预6个月时,有氧和抗阻运动组的HbA1c、SBP、DBP均低于干预前,抗阻运动组HOMA-IR低于干预前;干预12个月时,有氧和抗阻运动组的HbA1c、HOMA-IR、SBP、DBP均低于干预前,对照组HbA1c、SBP高于干预前,均差异有统计学意义(P0.05)。结论抗阻和有氧运动均能安全有效地改善社区IGR合并轻度高血压人群的HbA1c、血压、HOMA-IR,值得推广。
[Abstract]:Objective to study the control effect of different exercise ways on blood pressure in community pre-diabetic (IGR) population. Methods from June to August 2015, 83 residents with IGR combined with mild hypertension were selected from three community health service centers in Guilin. They were randomly divided into 3 groups. After one year's intervention and follow-up, 83 patients were selected. Finally, the complete data of 67 subjects were collected: resistance exercise group (22 cases), aerobic exercise group (23 cases) and control group (22 cases). During the intervention, the control group maintained the original lifestyle, the resistance group and the aerobic exercise group respectively carried out corresponding exercise intervention, about 50 min/, in the form of group training every other day. Fasting blood glucose, fasting insulin and glycosylated hemoglobin (HbA1c) were measured at 6 and 12 months after intervention, blood pressure was measured and insulin resistance index (HOMA-IR) was calculated. Results (1) there were significant differences in HOMA-IRR, SBP and DBP between different time points (F: 22.415, 9.28932.689 and 6.713, all P = 0.000). The difference was statistically significant (F _ (16.525) 4.241 ~ 26.436 and 4.653P ~ (0.000) 0.04 ~ 0.000 and 0.013). After intervention, the changes of HBA1cHOMA-IRMA-SBP+ DBP in the anti-resistance exercise group and aerobic exercise group were significantly lower than those in the control group (P < 0.05). During the intervention period, the indexes of the control group showed an overall upward trend. Although there was no significant difference between the two groups (P0.05), the decrease of HbA1cU HOMAIR in the resistance exercise group was higher than that in the aerobic exercise group, and there was no significant difference between the two exercise groups in different periods (P0.05), but the decrease of HbA1cHoma IR in the resistance exercise group was higher than that in the aerobic exercise group. The decrease of SBP in aerobic exercise group was lower than that in aerobic exercise group. (2) after 3 months of intervention, HbA1cHOMA-IRN DBP in aerobic and resistant exercise group was lower than that before intervention, SBP in aerobic exercise group was lower than that before intervention, and HbA1cSBPDBP in aerobic and resistant exercise group was lower than that before intervention for 6 months. HOMA-IR in the resistance exercise group was lower than that before intervention, and at 12 months after intervention, the DBP of HBA1cHoma / IRMA-SBP in the aerobic and resistant exercise groups was lower than that before the intervention, and that in the control group was higher than that before intervention (P0.05). Conclusion both resistance and aerobic exercise can improve HbA1c and HOMA-IRB in community IGR patients with mild hypertension safely and effectively, which is worth popularizing.
【作者单位】：广西医科大学第一附属医院;广西医科大学护理学院;广西中医药大学第一附属医院;
【基金】：广西医疗卫生技术研究与开发课题项目(No:S201413_03) 广西研究生教育创新计划项目(No:YCSZ2015111)
【分类号】：R544.1;R587.1

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