122例朗格汉斯细胞组织细胞增生症临床分析

发布时间：2018-07-06 17:18

本文选题：朗格汉斯细胞组织细胞增生症 + 临床分析　；参考：《中国医学科学院学报》2017年02期

【摘要】：目的探讨朗格汉斯细胞组织细胞增生症(LCH)的疾病特点。方法回顾性分析北京协和医院收治的122例LCH患者皮损表现、系统受累表现、影像学表现、实验室检查、免疫表型及治疗和预后情况。结果 LCH皮损形态多样,最常受累的器官为肺,其他易受累的部位有骨、皮肤、淋巴结、肝脏、脾脏、口腔、甲状腺等。多系统LCH患者较单系统LCH患者多见。单系统LCH多采用手术治疗,多系统LCH以联合化疗为主。结论 LCH临床表现多样,肺是最常见的受损器官;治疗可采用手术或化疗。
[Abstract]:Objective to investigate the characteristics of Langerhans cell histiocytosis (LCH). Methods the skin lesions, systemic involvement, imaging findings, laboratory examination, immunophenotype, treatment and prognosis of 122 patients with LCH in Peking Union Hospital were retrospectively analyzed. Results the lesions of LCH were varied, the most frequently involved organs were lung, and the other easily affected parts were bone, skin, lymph nodes, liver, spleen, mouth, thyroid and so on. Multisystem LCH patients were more common than single system LCH patients. Single system LCH was mostly treated by surgery, and multi-system LCH was mainly combined chemotherapy. Conclusion LCH has a variety of clinical manifestations and the lung is the most common damaged organ, which can be treated by surgery or chemotherapy.
【作者单位】：中国医学科学院北京协和医学院北京协和医院皮肤科;新乡市中心医院皮肤科;中国医学科学院北京协和医学院北京协和医院内分泌科;中国医学科学院北京协和医学院北京协和医院血液内科;
【分类号】：R597

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