成人糖尿病患者的同伴支持干预:糖化血红蛋白结果的Meta分析

发布时间：2018-07-11 11:50

本文选题：成人糖尿病 + Meta分析　；参考：《中国全科医学》2017年01期

【摘要】：目的同伴支持干预表现出对血糖控制的不同影响。本文旨在评估由糖尿病累及人群(患有该疾病人群或护理者)相互提供的同伴支持干预对成人糖尿病患者糖化血红蛋白(HbA_(1c)水平的影响。方法检索Ovid MEDLINE、Cochrane、CINAHL及Scopus多个数据库。检索时间为1960年1月—2015年11月。筛选以成年糖尿病患者接受同伴支持干预为试验组、接受其他类似护理方式为对照组的随机对照试验(RCT)。205条检索文献中有17条符合纳入标准。采用Cochrane偏倚风险评估工具进行质量评估。采用随机效应模型,计算组间基线HbA_(1c)水平变化的标准化均数差(SMD)。结果 7条文献中,3个整群RCT、14个RCT,共4 715例研究对象。与对照组相比,试验组HbA_(1c)水平改善,SMD为0.121[95%CI(0.026,0.217),P=0.01,χ~2=60.66%];HbA_(1c)水平改善了0.24%[95%CI(0.05%,0.43%)]。在以西班牙裔参与者为主要研究对象的文献中,HbA_(1c)水平改善了0.48%[95%CI(0.25%,0.70%),P0.001,I~2=17.12%];而以少数种族人群为主要研究对象的文献中,HbA_(1c)水平改善了0.53%[95%CI(0.32%,0.73%),P0.001,I~2=9.24%]。结论成人糖尿病患者间的同伴支持干预总体上而言,差异有统计学意义,但对HbA_(1c)水平改善效果并不显著。然而这些干预措施可能对改善少数种族群体、特别是西班牙裔群体的血糖控制特别有效。
[Abstract]:Objective Peer support intervention showed different effects on blood glucose control. The aim of this study was to evaluate the effects of peer support interventions by diabetic patients (persons with diabetes mellitus or caregivers) on the level of glycosylated hemoglobin (HbA1c) in adult diabetic patients. Methods multiple databases of Ovid MEDLINE CINAHL and Scopus were searched. The retrieval time is from January 1960 to November 2015. In the randomized controlled trial (RCT) .205 articles of adult diabetic patients receiving peer support intervention and other similar nursing methods as control group, 17 of them met the inclusion criteria. Cochrane bias risk assessment tool was used for quality assessment. The standardized mean difference (SMD) of baseline HbA( 1c) level was calculated by random effect model. Results among the 7 literatures, there were 3 cluster RCTs and 14 RCTs, totally 4 715 cases. Compared with the control group, the improvement of HbA1c level in the test group was 0.121 [95 CI (0.0260.217) P0. 01, 蠂 2 + 60.66%] HbA( 1c) improved by 0. 24% [95 CI (0. 05%) 0. 43%]. The level of HbA( 1c) was improved by 0.48% [95CI (0.250.70%), P 0.001 Igna 217.12%] in the literature with Hispanic participants as the main study object, while the HbA1c level was improved by 0.53% [95CI (0.32 / 0.73%)] P0.001I (29.24%) in the literature with minority ethnic groups as the main subjects of the study. The results showed that the level of HbA1c was improved by 0.48% [95 CI (0.25%) 0.70%] and 0.53% (95 CI (0.32%) 0.73%) in the literature with minority ethnic groups as the main subjects. Conclusion there was significant difference in peer support intervention among adult diabetic patients, but the effect on HbA1c level was not significant. However, these interventions may be particularly effective in improving blood glucose control among ethnic minorities, especially Hispanics.
【分类号】：R587.1

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