凉山彝族自治州2011-2015年艾滋病哨点吸毒人群HIV感染状况及影响因素

发布时间：2018-07-15 20:00

【摘要】：目的结合流行病学分析方法对凉山州2011-2015年艾滋病哨点吸毒人群艾滋病病毒(HIV)感染疫情进行分析,为制定当地艾滋病的防治策略提供科学依据。方法 2011-2015年,在凉山州7个国家级吸毒人群艾滋病监测哨点中,每年4-6月抽取口服、吸入和注射毒品的个体为监测对象。采用问卷调查收集人口学特征和相关行为特征信息。采用酶联免疫吸附试验和蛋白印迹试验进行HIV抗体阳性检测。采用SPSS 19.0统计学软件进行数据分析。结果 2011-2015年,共监测有效对象10 003人。2011-2015年,HIV阳性检出率分别为19.15%(449/2 345)、19.11%(369/1 931)、22.32%(431/1 931)、21.62%(411/1 901)、15.83%(300/1 895)。分析发现彝族[比值比(OR)=2.31,95%可信区间(CI):1.87~2.86]、共用针具(OR=8.60,95%CI:7.59~9.73)、文化程度低(初中vs高中及以上:OR=1.39,95%CI:0.97~2.01;小学或文盲vs高中及以上:OR=2.26,95%CI:1.60~3.19)能增加吸毒者感染HIV的风险;女性(OR=0.80,95%CI:0.68~0.94)和有固定性伴(OR=0.87,95%CI:0.76~0.99)感染HIV的风险比男性和没有固定性伴者低,年龄在51~70岁(OR=0.37,95%CI:0.23~0.60)感染HIV的风险较低。结论凉山彝族自治州吸毒人群HIV抗体阳性率较高,HIV在该人群中流行趋势严峻。
[Abstract]:Objective to analyze the epidemic situation of HIV infection among drug users in AIDS sentinel in Liangshan state from 2011 to 2015 in order to provide scientific basis for the strategy of AIDS prevention and control in Liangshan state. Methods from 2011 to 2015, the individuals who were administered orally, inhaled and injected drugs were selected from 7 national surveillance sentinels of drug users in Liangshan state from April to June of each year. Demographic characteristics and related behavioral characteristics were collected by questionnaire. Enzyme linked immunosorbent assay (Elisa) and Western blot assay were used to detect HIV antibody positive. SPSS 19.0 statistical software was used to analyze the data. Results in 2011-2015, the positive rate of HIV was 19.15% (449 / 2 345) and 22.32% (43.1 / 1,931) in 10 003 persons. The positive rate of HIV in 2011-2015 was 15.83% (3001.895). The analysis found that the Yi people [odds ratio (OR) 2.31 95% confidence interval (CI) 1.872.86], needle sharing (OR8.6095 CI: 7.599.73), low education level (middle school vs high school and above: 1.39995 CI: 0.972.01; primary school or illiterate vs high school or above) increased the risk of HIV infection among drug addicts; Women (OR0.80 / 95 CI: 0.68 0.94) and fixed partners (OR0.8795 CI: 0.760.99) had a lower risk of HIV infection than men and those without fixed partners, and the risk of HIV infection was lower in 51 or 70 years old (OR0.37 / 95 CIW 0.230.60). Conclusion the HIV antibody positive rate of drug users in Liangshan Yi Autonomous Prefecture is high.
【作者单位】：凉山州疾病预防控制中心;四川大学华西公共卫生学院健康与社会行为学系;
【基金】：国家自然科学基金(81703279) 四川省卫生和计划生育委员会科研课题(16PJ259) 凉山州艾滋病防治项目(H161236) 凉山州艾滋病新发感染评估模式探索项目(2014LSCDC002)~~
【分类号】：R512.91

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