2010-2014年重庆市渝中区教师人群血尿酸水平与血压的关系
发布时间：2018-07-16 15:42
【摘要】：目的了解重庆市渝中区教师人群高尿酸血症(HUA)的患病情况,探讨血尿酸与血压水平的关系。方法对2010、2012、2014年在重庆市人民医院健康管理(体检)中心进行健康体检的教师8354名体检报告结果进行调查分析。在研究血尿酸水平与血压的关系时,纳入体检指标完整、未服用药物的对象7120名;分析不同尿酸水平人群血压进展情况时,选择同时参加2010-2014年健康体检的同一人群1125人。结果 2010、2012、2014年重庆市渝中区教师人群HUA平均检出率为19.18%(1602/8354),男性HUA检出率(28.00%)高于女性(15.64%,P0.01)。2014与2010年比较,女性HUA检出率上升趋势明显,增长幅度高于男性。将不同性别研究对象按尿酸四分位水平分组,男性尿酸最高四分位组收缩压和舒张压较最低四分位组增加[分别为(134.8±16.8)比(130.0±17.8),(83.4±10.6)比(79.6±9.9)mm Hg],患高血压的风险增加至2.171倍;女性尿酸最高四分位组收缩压和舒张压较最低四分位组增加[分别为(135.1±22.4)比(122.2±17.2),(78.6±10.6)比(74.6±9.3)mm Hg],患高血压的风险增加至1.351倍(均P0.01)。随着尿酸水平增高,正常高值血压者进展为高血压的比例增加(P0.05)。结论重庆市渝中区教师人群中HUA的检出率呈上升趋势,高尿酸水平与血压水平相关。
[Abstract]:Objective to investigate the prevalence of hyperuricemia (Hua) in teachers in Yuzhong District of Chongqing and to explore the relationship between serum uric acid and blood pressure. Methods A total of 8354 teachers who underwent physical examination in the Center of Health Management (physical examination) of Chongqing people's Hospital in 2010 and 2014 were investigated and analyzed. In the study of the relationship between serum uric acid level and blood pressure, 7120 subjects who had not taken drugs were included in the physical examination, and 1125 people who took part in the health check-up from 2010 to 2014 were selected when analyzing the blood pressure progress of people with different uric acid levels. Results the average prevalence rate of Hua in teachers in Yuzhong District of Chongqing in 2014 was 19.18% (1602 / 8354), and that of male (28.00%) was higher than that of female (15.64g / P0.01) .Compared with 2010, the detection rate of HUA in female was higher than that in male. According to the quartile level of uric acid, the systolic and diastolic blood pressure in the highest quartile of uric acid group was higher than that in the lowest quartile group [(134.8 卤16.8) vs (130.0 卤17.8), (, 83.4 卤10.6) vs (79.6 卤9.9) mm Hg, respectively], and the risk of hypertension was 2.171 times higher than that in the lowest quartile group. Compared with the lowest quartile group, the systolic and diastolic blood pressure in the highest quartile group of uric acid increased [(135.1 卤22.4) vs (122.2 卤17.2), (, 78.6 卤10.6) mm Hg, respectively], and the risk of hypertension increased to 1.351 times (all P0.01). With the increase of uric acid level, the proportion of patients with normal high blood pressure progression to hypertension increased (P0.05). Conclusion the prevalence of UA in teachers in Yuzhong District of Chongqing is on the rise, and the level of high uric acid is related to blood pressure.
【作者单位】： 重庆市人民医院健康管理(体检)中心;
【基金】：重庆市卫生局医学科学技术研究项目(2010-2-283)
【分类号】：R544.1;R589.7
[Abstract]:Objective to investigate the prevalence of hyperuricemia (Hua) in teachers in Yuzhong District of Chongqing and to explore the relationship between serum uric acid and blood pressure. Methods A total of 8354 teachers who underwent physical examination in the Center of Health Management (physical examination) of Chongqing people's Hospital in 2010 and 2014 were investigated and analyzed. In the study of the relationship between serum uric acid level and blood pressure, 7120 subjects who had not taken drugs were included in the physical examination, and 1125 people who took part in the health check-up from 2010 to 2014 were selected when analyzing the blood pressure progress of people with different uric acid levels. Results the average prevalence rate of Hua in teachers in Yuzhong District of Chongqing in 2014 was 19.18% (1602 / 8354), and that of male (28.00%) was higher than that of female (15.64g / P0.01) .Compared with 2010, the detection rate of HUA in female was higher than that in male. According to the quartile level of uric acid, the systolic and diastolic blood pressure in the highest quartile of uric acid group was higher than that in the lowest quartile group [(134.8 卤16.8) vs (130.0 卤17.8), (, 83.4 卤10.6) vs (79.6 卤9.9) mm Hg, respectively], and the risk of hypertension was 2.171 times higher than that in the lowest quartile group. Compared with the lowest quartile group, the systolic and diastolic blood pressure in the highest quartile group of uric acid increased [(135.1 卤22.4) vs (122.2 卤17.2), (, 78.6 卤10.6) mm Hg, respectively], and the risk of hypertension increased to 1.351 times (all P0.01). With the increase of uric acid level, the proportion of patients with normal high blood pressure progression to hypertension increased (P0.05). Conclusion the prevalence of UA in teachers in Yuzhong District of Chongqing is on the rise, and the level of high uric acid is related to blood pressure.
【作者单位】： 重庆市人民医院健康管理(体检)中心;
【基金】：重庆市卫生局医学科学技术研究项目(2010-2-283)
【分类号】：R544.1;R589.7
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