重症肌无力病情评价常用量表的研究进展
发布时间：2018-07-30 08:27
【摘要】：正重症肌无力(myasthenia gravis,MG)是目前最常见的、最具特征性的神经-肌肉接头传递障碍的自身免疫性疾病。因神经-肌肉接头突触后膜上的乙酰胆碱受体受到自身抗体介导的、T细胞依赖性的免疫攻击,从而引起传递障碍而导致骨骼肌无力。MG可累及眼外肌、面部、颈部、延髓、四肢及呼吸肌等多个肌群,因受累部位的不同,其临床表现亦呈多样性,但均具有波动性及易疲劳性的特点~([1,2])。
[Abstract]:Positive myasthenia gravis (myasthenia gravis MG) is the most common and characteristic autoimmune disease of neuromuscular junction transmission disorder. Because the acetylcholine receptor on the postsynaptic membrane of the neuromuscular junction is attacked by autoantibody mediated T cell dependent immune attack, resulting in transmission disturbance, skeletal muscle weakness. MG may involve the extraocular muscle, face, neck, medulla oblongata. The clinical manifestations of multiple muscle groups, such as limbs and respiratory muscles, are diverse due to the different sites involved, but they all have the characteristics of volatility and fatigue.
【作者单位】： 锦州医科大学火箭军总医院研究生培养基地;中国人民解放军火箭军总医院神经内科;
【分类号】：R746.1
[Abstract]:Positive myasthenia gravis (myasthenia gravis MG) is the most common and characteristic autoimmune disease of neuromuscular junction transmission disorder. Because the acetylcholine receptor on the postsynaptic membrane of the neuromuscular junction is attacked by autoantibody mediated T cell dependent immune attack, resulting in transmission disturbance, skeletal muscle weakness. MG may involve the extraocular muscle, face, neck, medulla oblongata. The clinical manifestations of multiple muscle groups, such as limbs and respiratory muscles, are diverse due to the different sites involved, but they all have the characteristics of volatility and fatigue.
【作者单位】： 锦州医科大学火箭军总医院研究生培养基地;中国人民解放军火箭军总医院神经内科;
【分类号】：R746.1
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1 郑金瓯;莫雪安;马朝桂;;重症肌无力病人T淋巴细胞亚群的检测及与临床的关系[J];广西医学院学报;1993年04期
2 ;重症肌无力病人类固醇疗法所致股骨头缺血性坏死[J];青岛医学院学报;1992年01期
3 杨明山，徐金枝，李震中，，高波廷;1504例重症肌无力病人的临床资料分析和有关免疫学指标的测定[J];临床实用神经疾病杂志;1994年03期
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