广州市绝经后女性代谢综合征流行状况及其危险因素分析

发布时间：2018-08-07 13:44

【摘要】：目的掌握广州市绝经后女性代谢综合征(metabolic syndrome,MetS)流行状况及其相关危险因素。方法在全市随机抽取3 602名绝经后女性居民,进行流行病学调查、体格检查及实验室生化检测。统计不同年龄段及不同绝经年限女性MetS患病情况及其代谢异常组分分布,多因素logistic回归分析影响广州市居民MetS的危险因素。结果广州市绝经后女性MetS患病率为27.62%。随着年龄及绝经年限的增加,MetS患病率呈上升趋势;异常代谢组分中以"中心性肥胖+高血压+高三酰甘油(TG)"为主,合并3项、4项、5项代谢组分异常的患者分别占68.64%、27.34%和4.02%;随着绝经年限的增加,中心性肥胖、高血压和高血糖(或糖尿病)的发病率也呈现上升趋势;年龄增加、BMI升高、饮酒、高血压家族史、糖尿病家族史是广州市绝经后女性患MetS的危险因素,而规律性体育锻炼是其有效保护因素。结论广州市绝经后女性MetS的患病率较高,防控形势严峻。对绝经后女性应加强筛查及健康教育,根据MetS危险因素及早采取针对性预防和干预措施,提高绝经后女性的生活质量。
[Abstract]:Objective to investigate the prevalence and risk factors of metabolic syndrome in postmenopausal women in Guangzhou. Methods 3 602 postmenopausal female residents were randomly selected for epidemiological investigation, physical examination and laboratory biochemical examination. The prevalence of MetS and the distribution of abnormal metabolic components in women with different age and menopausal age were analyzed. The risk factors of MetS in Guangzhou residents were influenced by multivariate logistic regression analysis. Results the prevalence of MetS in postmenopausal women in Guangzhou was 27.62%. With the increase of age and menopausal age, the prevalence rate of MetS was on the rise, and the abnormal metabolic components were mainly "central obesity hypertension high triglyceride (TG)". The incidence of central obesity, hypertension and hyperglycemia (or diabetes) also increased with the increase of menopausal age. Family history of hypertension and diabetes mellitus were the risk factors of MetS in postmenopausal women in Guangzhou, and regular physical exercise was the effective protective factor. Conclusion the prevalence of MetS in postmenopausal women in Guangzhou is high and the situation of prevention and control is severe. Screening and health education should be strengthened for postmenopausal women and preventive and intervention measures should be taken as early as possible according to the risk factors of MetS in order to improve the quality of life of postmenopausal women.
【作者单位】：广州市疾病预防控制中心基层公共卫生部;广州医科大学附属广州市妇女儿童医疗中心临床数据研究中心;
【基金】：广州市医药卫生科技项目(编号:20151A011049,20141A011059)
【分类号】：R589

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