中老年男性肥胖类型与性激素关系研究

发布时间：2018-08-16 15:29

【摘要】：目的:探讨肥胖类型与性激素水平的关系。方法:采用横断面研究,以927例中老年男性为对象,统一获得其体质量指数(BMI)、腰高比(WHt R),测定血清总睾酮(TT)、性激素结合球蛋白(SHBG),并计算游离睾酮(c FT)和生物利用性睾酮(Bio-T),分析BMI、WHt R与性激素相关性,比较不同WHt R组性激素水平,并应用Logistic回归分析WHt R、肥胖类型与性激素低下关联。结果:WHt R与所有性激素指标TT、c FT、Bio-T和SHBG呈负相关(P0.05),而BMI仅与TT、SHBG呈负相关(P0.05);与低WHt R组(WHt R≤0.5)比,高WHt R组(WHt R0.5)血清TT、c FT、Bio-T和SHBG均显著下降(P0.05)。Logistic模型显示,双重肥胖组即BMI和WHt R都超标者,TT和c FT低下风险增加(P0.05),但仅有一般性肥胖或中心性肥胖与TT、c FT低下关联未显示统计学差异(P0.05)。结论:一般性肥胖和中心性肥胖共存是中老年男性血清TT、c FT低下的危险因素。
[Abstract]:Objective: to study the relationship between obesity type and sex hormone level. Methods: a cross-sectional study was conducted in 927 middle-aged and aged men. The body mass index (BMI), waist height ratio (WHt R), serum total testosterone (TT), sex hormone binding globulin (SHBG), free testosterone (c FT) and bioavailability testosterone (Bio-T) were determined, and the correlation between sex hormones and sex hormones was analyzed, and the sex hormone levels in different WHt R groups were compared. Logistic regression analysis was used to analyze WHt R.The obesity type was associated with low sex hormone. Results compared with the low WHt R group (WHt R 鈮，

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