以发热肌酸激酶升高为首发表现的免疫介导性坏死性肌病1例
发布时间:2018-08-19 11:44
【摘要】:正他汀类药物是治疗心血管疾病常用药物之一,能够显著降低低密度脂蛋白水平[1]。随着他汀类药物在临床上的广泛应用,其常见不良反应也已广为认识,但尚需提高对少见不良反应的认识[2]。本文收治1例以发热、横纹肌溶解为首发表现,病理证实为免疫介导坏死性肌病,排除其他原因,诊断为瑞舒伐他汀(rosuvastatin)所致肌溶解,现报道如下,以期望能够提高临床医生对药物相关不良反应的认识,
[Abstract]:Orthostatin is one of the commonly used drugs in the treatment of cardiovascular disease, which can significantly reduce the low density lipoprotein level [1]. With the wide use of statins in clinical practice, its common adverse reactions have been widely recognized, but it is necessary to improve the understanding of rare adverse reactions [2]. A case with fever, rhabdomyolysis as the first manifestation, immuno-mediated necrotic myopathy confirmed by pathology, excluding other causes, was diagnosed as myolysis caused by recuvastatin (rosuvastatin). The present report is as follows. In the hope of raising clinicians' awareness of drug-related adverse reactions,
【作者单位】: 北京大学第一医院感染疾病科;北京大学第一医院神经内科;
【分类号】:R593.2
[Abstract]:Orthostatin is one of the commonly used drugs in the treatment of cardiovascular disease, which can significantly reduce the low density lipoprotein level [1]. With the wide use of statins in clinical practice, its common adverse reactions have been widely recognized, but it is necessary to improve the understanding of rare adverse reactions [2]. A case with fever, rhabdomyolysis as the first manifestation, immuno-mediated necrotic myopathy confirmed by pathology, excluding other causes, was diagnosed as myolysis caused by recuvastatin (rosuvastatin). The present report is as follows. In the hope of raising clinicians' awareness of drug-related adverse reactions,
【作者单位】: 北京大学第一医院感染疾病科;北京大学第一医院神经内科;
【分类号】:R593.2
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