高血压合并糖尿病患者基于腹部CT指标的危险因素分析

发布时间：2018-09-18 09:54

【摘要】：目的:分析高血压合并糖尿病患者腹部CT的图像特征及其他相关指标,探讨高血压人群并发糖尿病的危险因素。方法:回顾性分析1 962例在东南大学附属中大医院行腹部CT平扫的患者临床资料,分为正常对照组(n=858)、高血压组(n=732)、糖尿病组(n=128)及高血压合并糖尿病组(n=244)。测量所有受检者腹部CT相关指标包括脂肪肝、胰/脾CT值、内脏脂肪(VAT)面积、皮下脂肪(SAT)面积、VAT/SAT面积值、腰大肌CT值及腹主动脉钙化评分。应用Logistic回归分析筛选高血压人群并发糖尿病的危险因素。结果:Logistic回归分析显示,脂肪肝、甘油三酯水平升高、高密度脂蛋白水平降低、高血压分级增高、腰围增大及腰大肌CT值减低是高血压人群发生糖尿病的危险因素。结论:脂肪肝、增高的高血压分级、肌肉脂肪浸润程度、腰围增大和血脂异常均会增加高血压患者糖尿病的发病率。
[Abstract]:Objective: to investigate the risk factors of hypertension complicated with diabetes mellitus by analyzing the image features and other related indexes of abdominal CT in patients with hypertension and diabetes. Methods: the clinical data of 1 962 patients undergoing CT scan were retrospectively analyzed. They were divided into normal control group (n = 858), hypertension group (n = 732), diabetes mellitus group (n = 128) and hypertension with diabetes group (n = 244). Abdominal CT were measured including fatty liver, pancreatic / splenic CT, visceral fat (VAT) area, subcutaneous fat (SAT) area, CT value of psoas major muscle and abdominal aortic calcification score. Logistic regression analysis was used to screen the risk factors of diabetes mellitus in hypertensive population. Results the results of Logistic regression analysis showed that the increase of triglyceride level, the decrease of high density lipoprotein level, the increase of hypertension grade, the increase of waist circumference and the decrease of CT value of psoas major muscle were the risk factors of diabetes in patients with hypertension. Conclusion: fatty liver, increased grade of hypertension, degree of muscle fat infiltration, increase of waist circumference and dyslipidemia will increase the incidence of diabetes mellitus in patients with hypertension.
【作者单位】： 东南大学医学院;东南大学附属中大医院放射科;
【基金】：国家自然科学基金资助课题(81371538)
【分类号】：R544.1;R587.1
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本文编号：2247538