中老年女性骨质疏松患者升主动脉壁弹性指标与骨密度的相关性

发布时间：2018-10-16 11:37

【摘要】：目的探讨中老年女性骨质疏松(OP)患者升主动脉壁弹性指标与骨密度(BMD)的相关性。方法采用双能X线骨密度仪检测受试者BMD值,选取40岁以上闭经女性OP患者74例;应用组织速度成像技术(TVI)测量升主动脉瓣上3 cm处前壁组织的弹性指标,包括扩张速度Sao、回缩速度Eao、Aao、扩张加速度(AC)、加速时间(Tac),按每10岁一个年龄段分为5组。结果女性BMD及Sao、Eao、Aao、AC随年龄的增长均呈下降趋势;而Tac呈延长趋势;女性各年龄组BMD与升主动脉弹性参数Bonferroni两两比较,除外BMD及Sao、Eao、Aao、AC均在70~79岁与80岁以上组间无统计学意义(P0.05);BMD在60~69岁与70~79岁组、Sao在40~49岁与50~59岁组、Eao、Aao与AC在50~59岁与60~69岁组、Tac在60~69岁与70~79岁组间差异均无统计学意义(P0.05)外,其余组间均有统计学意义(P0.001);女性OP患者BMD与升主动脉前壁各参数均有相关关系(P0.001),且与Eao,Aao,Sao,AC呈正相关,与Tac呈负相关。结论升主动脉壁弹性指标与BMD之间存在相关性,中老年女性OP患者随着年龄增长,动脉弹性减低,动脉硬化危险性增加,对OP患者进行动脉弹性指标的检测,可能对预防原发性OP有重要意义,为早期诊断、预防和治疗提供理论依据。
[Abstract]:Objective to investigate the correlation between the index of ascending aortic wall elasticity and bone mineral density (BMD) in aged women with osteoporosis (OP). Methods BMD was measured by dual energy X-ray absorptiometry in 74 women with amenorrhea over 40 years of age, and tissue velocity imaging (TVI) was used to measure the elastic index of anterior wall tissue at 3 cm of ascending aortic valve. The (AC), acceleration time (Tac),) was divided into 5 groups according to each age group of 10 years old, including expansion velocity, Sao, retraction velocity, Eao,Aao, expansion acceleration, (AC), acceleration time. Results both BMD and Sao,Eao,Aao,AC showed a downward trend with the increase of age, while Tac showed a tendency of prolonging. BMD and Bonferroni of ascending aorta were compared with each other in different age groups. Except for BMD and Sao,Eao,Aao,AC, there was no significant difference between the groups aged 70 to 79 years and over 80 years old (P0.05). There was no significant difference between the groups of); BMD aged 60 / 69 and 70 / 79, Sao at 40 / 49 and 50 / 59, Eao,Aao and AC at 50 / 59 and 60 / 69, and Tac at 60 / 69 and 70 / 79 (P0.05). There was a significant correlation between BMD and anterior wall parameters of ascending aorta in female patients with OP (P0. 001), and there was a positive correlation with Eao,Aao,Sao,AC and a negative correlation between BMD and Tac. Conclusion there is a correlation between the index of ascending aortic wall elasticity and BMD. The arterial elasticity decreases and the risk of arteriosclerosis increases with the increase of age in middle-aged and elderly women with OP. The arterial elasticity index is detected in OP patients. It may play an important role in the prevention of primary OP and provide theoretical basis for early diagnosis, prevention and treatment.
【作者单位】：一汽总医院吉林大学第四医院电诊科;
【基金】：吉林省卫生厅科研立项(No.2011-I-083)
【分类号】：R580

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