文化程度与燃煤型氟中毒关系的病例对照研究

发布时间：2018-10-17 18:02

【摘要】：目的探讨文化程度与燃煤型氟中毒的关系。方法采用1∶1配对病例对照研究,在贵州省织金县招募200例氟中毒患者及性别、年龄(±3岁)匹配的200例对照,通过面对面访谈的形式进行问卷调查。调查内容包括:一般情况、膳食调查等。采用Logistic回归分析分析文化程度与燃煤型氟中毒的关系。结果多因素Logistic回归分析:钙摄入量和较高的文化程度是氟中毒的保护因素(P0.05),辣椒玉米使用未淘洗和炉灶未改良是氟中毒的危险因素(P0.05)。进一步分析发现,与文盲组比较,初中组和高中及以上组差异有统计学意义(P0.05)。结论文化程度越高,燃煤型氟中毒患病危险性越低。除了改炉改灶等降低氟暴露水平的措施以外,应重视并加强基础教育,提高病区居民文化水平,以利于燃煤型氟中毒的综合防治。
[Abstract]:Objective to explore the relationship between education level and coal-burning fluorosis. Methods A 1:1 matched case-control study was conducted to investigate 200 fluorosis patients and 200 matched controls with age (卤3 years) in Zhijin County, Guizhou Province. A questionnaire survey was conducted in the form of face to face interview. The contents of the investigation include: general situation, dietary survey and so on. Logistic regression analysis was used to analyze the relationship between education level and coal-burning fluorosis. Results Logistic regression analysis showed that calcium intake and higher education level were the protective factors of fluorosis (P0.05), and the risk factors of fluorosis were unwashed pepper maize and unimproved stove (P0.05). Further analysis found that, compared with the illiterate group, junior high school group and high school and above group differences were statistically significant (P0.05). Conclusion the higher the education level, the lower the risk of coal-burning fluorosis. Besides the measures to reduce the level of fluoride exposure, we should pay attention to and strengthen the basic education and raise the cultural level of the residents in the disease area, so as to benefit the comprehensive prevention and treatment of coal-burning fluorosis.
【作者单位】：遵义医学院公共卫生学院预防医学实验教学中心;遵义医学院附属医院药剂科;贵州省织金县疾病预防控制中心慢性病防治科;
【基金】：国家自然科学基金资助项目(81460497) 遵义医学院博士启动基金(A-706)
【分类号】：R595

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