肥胖对男性生殖细胞功能的影响及其机制研究进展
发布时间:2018-10-19 19:33
【摘要】:肥胖可导致男性生殖功能下降,表现为精子数量和精液质量下降、附睾中精子运动功能下降。其发生机制包括肥胖影响性激素分泌、促进生精细胞凋亡、促进氧化应激和导致生殖细胞表观遗传学改变。
[Abstract]:Obesity can lead to the decrease of male reproductive function, which is manifested by the decrease of sperm quantity and semen quality, and the decrease of sperm motility in epididymis. The mechanisms include obesity affecting the secretion of sex hormones, promoting the apoptosis of spermatogenic cells, promoting oxidative stress and leading to epigenetic changes of germ cells.
【作者单位】: 延边大学医学院;吉林医药学院公共卫生学院;
【基金】:国家自然科学基金项目(81472964) 吉林省自然科基金项目(201501012065C)
【分类号】:R589.2
本文编号:2282149
[Abstract]:Obesity can lead to the decrease of male reproductive function, which is manifested by the decrease of sperm quantity and semen quality, and the decrease of sperm motility in epididymis. The mechanisms include obesity affecting the secretion of sex hormones, promoting the apoptosis of spermatogenic cells, promoting oxidative stress and leading to epigenetic changes of germ cells.
【作者单位】: 延边大学医学院;吉林医药学院公共卫生学院;
【基金】:国家自然科学基金项目(81472964) 吉林省自然科基金项目(201501012065C)
【分类号】:R589.2
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