2294例生殖异常者的染色体核型分析

发布时间：2018-10-24 17:11

【摘要】：目的:探讨生殖异常者与染色体核型异常的关系。方法:对2 294例生殖异常者的外周血进行培养并行常规G显带、核型分析。结果:2 294例生殖异常者中检出221例染色体核型异常,核型异常率为9.63%,其中常染色体结构异常33例,性染色体数目异常26例,性染色体结构或功能异常6例,染色体多态性核型156例。结论:染色体核型异常是导致生殖异常的重要原因。
[Abstract]:Objective: to study the relationship between abnormal reproduction and abnormal karyotype. Methods: the peripheral blood of 2 294 cases with abnormal reproduction was cultured with G banding and karyotype analysis. Results: 221 cases of abnormal karyotype were detected in 2 294 cases of abnormal reproduction. The abnormal rate of karyotype was 9.63 cases. Among them, 33 cases were abnormal in autosomal structure, 26 cases were abnormal in the number of sex chromosomes, 6 cases were abnormal in structure or function of sex chromosome. There were 156 cases of chromosome polymorphic karyotype. Conclusion: abnormal chromosome karyotype is an important cause of reproductive abnormality.
【作者单位】： 河北医科大学第四医院分子生物学研究室;
【分类号】：R596
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本文编号：2292017