甘南藏族人群盐敏感性与代谢综合征的关系研究
发布时间:2018-11-18 19:05
【摘要】:目的探讨甘南藏族人群盐敏感性(SS)与代谢综合征(MS)的关系。方法于2013年6月—2014年11月,在甘肃省甘南藏族自治州夏河县和合作县选取原发性高血压病1级者737例、非高血压者631例。收集受试者的性别、年龄、身高、体质量、腰围、臀围、血压、空腹血糖(FPG)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)等临床资料,并计算BMI。采用我国改良后的急性盐负荷试验方法,根据Sullivan标准判定是否存在SS;分别根据中华医学会糖尿病学分会(CDS)、国际糖尿病联盟(IDF)、美国国家胆固醇教育计划成人治疗组第三次报告(NCEP-ATPⅢ)制定的诊断标准,判定是否患MS。结果甘南藏族高血压者、非高血压者的SS检出率分别为72.9%(537/737)、64.5%(407/631),高血压者高于非高血压者,差异有统计学意义(P0.05)。根据CDS、IDF、NCEP-ATPⅢ诊断标准,高血压者的MS检出率分别为47.9%(353/737)、55.0%(405/737)、37.7%(278/737),非高血压者的MS检出率分别为3.5%(22/631)、15.8%(100/631)、4.8%(30/631)。是否存在SS高血压者、非高血压者根据CDS、IDF、NCEP-ATPⅢ的MS检出率比较,差异均无统计学意义(P0.05)。SS高血压者根据CDS的BMI偏高、根据NCEP-ATPⅢ的腰围偏高检出率低于非SS高血压者,差异有统计学意义(P0.05);SS非高血压者TG偏高、根据CDS的血糖偏高、根据IDF的血糖偏高、根据NCEP-ATPⅢ的血糖偏高检出率低于非SS非高血压者,根据IDF的腰围偏高、根据NCEP-ATPⅢ的腰围偏高检出率高于非SS非高血压者,差异有统计学意义(P0.05)。结论甘南藏族高血压人群和非高血压人群的SS、MS检出率均较高,SS与MS间无直接关系,但MS部分组分与SS间存在统计学关联,需进一步研究证实。
[Abstract]:Objective to investigate the relationship between salt-sensitive (SS) and metabolic syndrome (MS) in Gannan Tibetan population. Methods from June 2013 to November 2014, 737 cases of grade 1 essential hypertension and 631 cases of non-hypertension were selected from Xiahe County and Hehe County, Gansu Autonomous Prefecture of Gansu Province. The clinical data of sex, age, height, body mass, waist circumference, hip circumference, blood pressure, fasting blood glucose, (FPG), triacylglycerol, (TG), high density lipoprotein cholesterol (HDL-C) were collected, and BMI. was calculated. The modified acute salt load test method was used to determine the existence of SS; according to the Sullivan standard. According to the diagnostic criteria established by the third report (NCEP-ATP 鈪,
本文编号:2340907
[Abstract]:Objective to investigate the relationship between salt-sensitive (SS) and metabolic syndrome (MS) in Gannan Tibetan population. Methods from June 2013 to November 2014, 737 cases of grade 1 essential hypertension and 631 cases of non-hypertension were selected from Xiahe County and Hehe County, Gansu Autonomous Prefecture of Gansu Province. The clinical data of sex, age, height, body mass, waist circumference, hip circumference, blood pressure, fasting blood glucose, (FPG), triacylglycerol, (TG), high density lipoprotein cholesterol (HDL-C) were collected, and BMI. was calculated. The modified acute salt load test method was used to determine the existence of SS; according to the Sullivan standard. According to the diagnostic criteria established by the third report (NCEP-ATP 鈪,
本文编号:2340907
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