健康体检人群中颈围与代谢综合征的相关性研究

发布时间：2018-12-12 04:07

【摘要】：目的:代谢综合征(metabolic syndrome,MS)是由多种代谢成分异常聚集并以代谢紊乱为特征的复杂症候群,随其发病率的升高,大大增加了糖尿病、心血管等疾病的发生,已成为全世界关注的焦点。近年来,随着人们对MS认识的不断完善、深入,越来越多的研究显示:颈围与MS具有一定的相关性。本研究旨在探讨颈围预测MS的可行性和价值,并确定颈围预测MS的最佳切点。方法:收集2016年6月至2016年11月于邢台市人民医院体检中心进行健康体检并资料完整者809例作为研究对象。记录患者一般情况:性别、年龄、职业、既往病史、体格测量指标(身高、体重、血压、颈围、腰围),计算体重指数(BMI)。实验室指标(血糖、甘油三酯、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、总胆固醇、转氨酶、肌酐、血尿酸)。使用统计软件SPSS17.0对以上数据进行分析。结果:1本研究809名研究对象中,MS总检出率为19.16%,其中男性检出率22.37%,女性检出率16.43%,男性MS检出率高于女性,差异有统计学意义,不同年龄组间检出率差异在男女性中均有统计学意义,且检出率随年龄增加呈上升趋势。2随着颈围四分位数的增加,男性女性中体重、BMI、腰围、收缩压、舒张压、TG的均值是增加的,差异均有统计学意义。3男性颈围预测MS的最佳切点为38.5cm,女性颈围预测MS的最佳切点为34.5cm。结论:1颈围增大与代谢综合征的发病密切相关,对MS的早期预测及预防有重要意义。2男性颈围38.5cm、女性颈围34.5cm可作为预测MS的最佳切点。
[Abstract]:Objective: metabolic syndrome (metabolic syndrome,MS) is a complex syndrome characterized by abnormal accumulation of various metabolic components and characterized by metabolic disorder. With the increase of its incidence, the incidence of diabetes, cardiovascular and other diseases is greatly increased. Has become the focus of attention around the world. In recent years, with the continuous improvement of people's understanding of MS, more and more research shows that neck circumference and MS have a certain correlation. The purpose of this study was to explore the feasibility and value of neck circumference in predicting MS and to determine the optimal tangent point of neck circumference for MS prediction. Methods: from June 2016 to November 2016, 809 patients with complete data were collected from the physical examination Center of Xingtai people's Hospital. Record patient's general situation: gender, age, occupation, past medical history, physical measurements (height, weight, blood pressure, neck circumference, waist circumference), calculate body mass index (BMI).) Laboratory parameters (blood glucose, triglyceride, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), total cholesterol, transaminase, creatinine, uric acid). Use the statistical software SPSS17.0 to analyze the above data. Results: 1 among 809 subjects in this study, the total detection rate of MS was 19.16. The detection rate of male was 22.37 and that of female was 16.43. The detection rate of MS in male was higher than that in female, the difference was statistically significant. The difference of detection rate among different age groups was statistically significant in both sexes, and the positive rate increased with the increase of age. 2 with the increase of cervical circumference quartile, weight, BMI, waist circumference, systolic blood pressure, diastolic blood pressure in male and female. The mean value of TG was increased, and the difference was statistically significant. 3 the best point of neck circumference for predicting MS was 38.5 cm for male and 34.5 cm for MS in female. Conclusion: 1 the increase of neck circumference is closely related to the onset of metabolic syndrome, which is of great significance for early prediction and prevention of MS. 2male neck circumference 38.5 cm, female neck circumference 34.5cm can be used as the best point to predict MS.
【学位授予单位】：河北医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R589

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