绝经后骨质疏松症证素与性激素、骨密度、体重指数的相关性研究

发布时间：2019-01-14 15:48

【摘要】：目的:基于证素辨证学制定证候辨证量表,对绝经后骨质疏松症(PMOP)患者进行证素特征分析,针对PMOP证素与性激素水平、骨密度、体重指数开展相关性研究,为建立PMOP证素诊断模型提供依据。方法:应用“证候辨证素量表”,将120例PMOP患者依据证素特征,分为肾虚、肾虚+痰湿、肾虚+血瘀、肾虚+气滞4组,并调查性激素、骨密度、体重指数,采用SPSS17.0统计软件进行统计描述,探讨证素与性激素、骨密度、体重指数的相关性。结果:性激素、骨密度、体重指数是PMOP的特征性指标,与肾、气滞、痰湿、血瘀证素密切相关。结论:1.绝经后骨质疏松症以病位证素肾为主,气滞、痰湿、血瘀为常见病性证素。2.PMOP证素肾、痰湿、气滞、血瘀与Pro、T、E2成负相关性,与LH、FSH、PRL成正相关性。3.PMOP证素与BMI相关,BMI对于骨质疏松症具有正负双向作用。4.骨密度与PMOP证素成相关性变化,不同证素骨密度含量迥异。
[Abstract]:Objective: to make syndrome differentiation scale based on syndrome element differentiation to analyze the characteristics of syndrome element in postmenopausal osteoporosis (PMOP) patients, and to study the correlation between PMOP syndromes and sex hormone level, bone mineral density, body mass index. To provide the basis for establishing the diagnosis model of PMOP syndrome element. Methods: 120 patients with PMOP were divided into 4 groups according to their syndromes: kidney deficiency, phlegm dampness, kidney deficiency and blood stasis, and kidney deficiency qi stagnation. Sex hormone, bone mineral density and body mass index were investigated. The correlation between sex hormone, bone mineral density (BMD) and body mass index (BMI) was investigated by SPSS17.0 software. Results: sex hormone, bone mineral density and body mass index were characteristic indexes of PMOP, which were closely related to kidney, qi stagnation, phlegm dampness and blood stasis syndrome factors. Conclusion: 1. Postmenopausal osteoporosis is characterized by kidney syndrome, Qi stagnation, phlegm dampness and blood stasis. 2.PMOP syndrome has negative correlation with Pro,T,E2, phlegm dampness, qi stagnation and blood stasis. PRL showed positive correlation. 3.PMOP syndromes were correlated with BMI, and BMI had positive and negative effects on osteoporosis. 4. 4. Bone mineral density (BMD) was correlated with PMOP syndromes, and the BMD content of different syndromes was very different.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R580

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