极低频电磁场对SD大鼠造血系统的影响

发布时间：2019-01-23 19:09

【摘要】：为研究极低频电磁场(ELF-EMFs)对SD大鼠造血系统的影响,从而合理利用电力资源预防疾病的发生,将128只SD雄性大鼠随机分成2组,即暴露组和对照组,将暴露组大鼠置于磁感应强度为100μT、频率为50 Hz的极低频电磁场暴露装置中,每天暴露20 h,连续暴露12周;而对照组SD大鼠不接受极低频电磁场的暴露。分别在暴露前和暴露12周后对SD大鼠的血常规进行检测。在暴露结束后,取SD大鼠的股骨和脾脏进行苏木素-伊红染色,并观察其结构。此外,还对SD大鼠的骨髓活检进行了细胞学分析,并对其脾脏组织中的细胞分类进行了检测。结果表明:暴露组与对照组SD大鼠的外周血液白细胞计数、中性粒细胞比例和淋巴细胞比例没有统计学差异;且极低频电磁场暴露对SD大鼠的红细胞计数、血红蛋白浓度和血小板计数没有影响;SD大鼠骨髓以及脾脏的苏木素-伊红染色显示极低频电磁场暴露对其造血器官结构没有影响。骨髓活检结果显示极低频磁场暴露并未导致SD大鼠的骨髓发生细胞学异常,脾脏细胞分类计数表明暴露组与对照组之间各类细胞分类并无差异。由此可得结论:磁感应强度为100μT、频率为50 Hz的极低频电磁场暴露对SD大鼠的造血系统没有影响。
[Abstract]:In order to study the effect of very low frequency electromagnetic field (ELF-EMFs) on the hematopoietic system of SD rats and to make rational use of power resources to prevent the occurrence of diseases, 128 male SD rats were randomly divided into two groups: exposed group and control group. Rats in the exposure group were exposed to an extremely low frequency electromagnetic field with a magnetic induction intensity of 100 渭 T and a frequency of 50 Hz for 20 hours per day for 12 weeks. SD rats in the control group were not exposed to very low frequency electromagnetic fields. The blood routine of SD rats was detected before and 12 weeks after exposure. After exposure, the femur and spleen of SD rats were stained with hematoxylin-eosin and their structures were observed. In addition, the bone marrow biopsy of SD rats was analyzed by cytology, and the cell classification in spleen tissue was also detected. The results showed that there was no significant difference in peripheral blood leucocyte count, neutrophil percentage and lymphocyte ratio between exposed group and control group in SD rats. Moreover, very low frequency electromagnetic field exposure had no effect on erythrocyte count, hemoglobin concentration and platelet count in SD rats. Hematoxylin-eosin staining in bone marrow and spleen of SD rats showed that very low frequency electromagnetic field exposure had no effect on hematopoietic organ structure. The results of bone marrow biopsy showed that very low frequency magnetic field exposure did not result in cytological abnormalities in bone marrow of SD rats. The spleen cell classification showed no difference between the exposed group and the control group. It is concluded that the exposure of extremely low frequency electromagnetic fields with a magnetic induction intensity of 100 渭 T and a frequency of 50 Hz has no effect on the hematopoietic system of SD rats.
【作者单位】：中国电力科学研究院电网环境保护国家重点实验室;华中科技大学同济医学院附属同济医院心内科;
【基金】：国家电网公司重大科技项目(GY71-16-008)~~
【分类号】：R594.8

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