不同类型肥胖与骨质疏松症的研究

发布时间：2019-02-12 23:28

【摘要】：目的旨在分析肥胖与骨质疏松症的关系,为肥胖与骨质疏松症的防治提供切实可信的数据。方法选取2014年1月至2015年1月在哈尔滨医科大学附属第二医院体检中心进行体检人员1192例,测定甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)、空腹血糖(FBG)的值。采用双能X线骨密度扫描双侧股骨及腰椎进行骨密度检测,根据骨密度T值分为骨量正常组、骨量减少组和骨质疏松组并结合身高、体重、血压、腰围等分为全身性肥胖、复合型肥胖、中心性肥胖,使用t检验和χ~2检验各组间有无统计学差异,对检测结果进行分析。结果在男性群体中50~59岁年龄组骨质疏松检出率明显升高(12.06%),80~89岁组达到最高(16.67%);女性群体中随年龄增长骨质疏松检出率有所增加,而70~79岁组骨质疏松的检出率最高为54.55%。在骨量正常组、骨量减少组及骨质疏松组3组中空腹血糖、甘油三酯和低密度脂蛋白胆固醇组间比较有差异,且具有统计学意义(P0.05)。合并一种代谢异常与骨质疏松的研究中,高血糖、血脂异常合并骨质疏松组间比较差异显著,有统计学意义;两种代谢异常合并骨质疏松组间比较差异显著,有统计学意义(P0.05)。复合型肥胖、中心性肥胖合并骨质疏松组间比较差异显著,有统计学意义(P0.05)。结论不同类型的肥胖与骨质疏松的关系并不一致。
[Abstract]:Objective to analyze the relationship between obesity and osteoporosis and to provide reliable data for the prevention and treatment of obesity and osteoporosis. Methods from January 2014 to January 2015, 1192 medical examiners were selected from the second affiliated Hospital of Harbin Medical University to determine the triglyceride (TG), total cholesterol (TC), low density lipoprotein (LDL-C). High density lipoprotein (HDL-C), fasting blood glucose (FBG) value. Bone mineral density (BMD) of femur and lumbar vertebrae were measured by dual energy X-ray BMD scan. According to BMD T value, BMD was divided into normal bone mass group, osteopenia group and osteoporosis group, combined with height, weight, blood pressure, waist circumference and so on. Complex obesity, central obesity, t test and 蠂 ~ 2 test were used to test whether there were statistical differences between the groups, the results were analyzed. Results the prevalence rate of osteoporosis in the 50-59 age group was significantly higher (12.06%), and the highest in the 80-89 age group (16.67%). The detection rate of osteoporosis increased with age in female population, and the highest rate of osteoporosis was 54.55 in 70 ~ 79 years old group. There were significant differences in fasting blood glucose, triglyceride and low density lipoprotein cholesterol among the three groups in the normal bone mass group, the osteopenia group and the osteoporosis group (P0.05). In the study of hyperglycemia, hyperglycemia and dyslipidemia combined with osteoporosis, there were significant differences between the two groups. The difference between the two metabolic abnormalities combined with osteoporosis group was significant (P0.05). Complex obesity, central obesity combined with osteoporosis group differences were significant (P0.05). Conclusion the relationship between different types of obesity and osteoporosis is not consistent.
【作者单位】：哈尔滨医科大学附属第二医院;
【基金】：国家自然科学基金项目(81301292)
【分类号】：R580

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