三种影像学检查联用在继发性甲状旁腺功能亢进症术前定位的诊断价值研究

发布时间：2019-08-08 07:52

【摘要】：目的:研究MRI、~(99m)锝-甲氧基异丁基异腈(~(99m)Tc-MIBI)核素显像及彩色多普勒超声等3种影像学联用在继发性甲状旁腺功能亢进症(SHPT)术前定位的诊断价值。方法:回顾性分析2010-2017年期间首次行甲状旁腺切除术的72例SHPT患者,72例患者均通过上述3种影像学对病变甲状旁腺进行术前定位。以手术后病理诊断结果为金标准,分别统计出3种影像学检查联用及各自所诊断甲状旁腺的确诊数及误诊数,并计算敏感度及特异度,通过SPSS 19.0软件运用率的χ~2检验将3种影像学检查联用同每种影像学方法的敏感度及特异度分别加以对比分析。结果:术后病理所报甲状旁腺共282枚,MRI、~(99m)Tc-MIBI核素显像、彩色多普勒超声及3种影像学检查联用的敏感度分别为72.70%、47.52%、44.33%、82.27%;特异度分别为78.16%、91.75%、95.14%、67.96%;3种影像学联用的敏感度大于各自的敏感度,均差异有统计学意义,而3种影像学联用的特异度均小于各自的特异度,差异有统计学意义。结论:MRI、~(99m)Tc-MIBI核素显像及彩色多普勒超声等3种影像学检查联用对病变甲状旁腺术前定位的诊断价值较高,可有效辅助SHPT的手术治疗。
[Abstract]:Objective: to study the diagnostic value of MRI,~ _ (99m) technetium-methoxyisobutylisonitrile (~ (99m) Tc-MIBI) radionuclide imaging and color Doppler ultrasound in the preoperative localization of secondary hyperparathyropathy (SHPT). Methods: 72 patients with SHPT who underwent parathyroidectomy for the first time from 2010 to 2017 were analyzed retrospectively. the preoperative localization of parathyroidectomy was performed in 72 patients with parathyroidectomy. According to the results of pathological diagnosis after operation as the gold standard, the number of diagnosis and misdiagnosis of parathyroid gland were counted, and the sensitivity and specificity were calculated. The sensitivity and specificity of the three imaging examinations combined with each imaging method were compared and analyzed by the Chi ~ 2 test of the operation rate of SPSS 19.0 software. The sensitivity and specificity of the three imaging examinations were compared with those of each imaging method, and the sensitivity and specificity of each imaging method were compared and analyzed by means of the Chi ~ 2 test of the operation rate of the three imaging examinations. Results: the sensitivity, specificity, specificity and specificity of MRI,~ (99m) Tc-MIBI radionuclide imaging, color Doppler ultrasound and three kinds of imaging were 72.70%, 47.52%, 44.33%, 82.27%, 78.16%, 91.75%, 95.14% and 67.96%, respectively. the sensitivity, specificity, specificity and specificity were 72.70%, 47.52%, 44.33%, 82.27%, 78.16%, 91.75%, 95.14% and 67.96%, respectively. The sensitivity of the three kinds of imaging combination was higher than that of their respective ones, and the difference was statistically significant, while the specificity of the three kinds of imaging combination was less than their respective specificity, and the difference was statistically significant. Conclusion: the combination of MRI,~ _ (99m) Tc-MIBI radionuclide imaging and color Doppler ultrasound is of high diagnostic value in the preoperative localization of parathyroid lesions and can effectively assist the surgical treatment of SHPT.
【作者单位】：北京大学民航临床医学院民航总医院耳鼻咽喉头颈外科;
【分类号】：R582.1

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