基于肠道微生态探讨黄连素在代谢性疾病中的抗炎作用(英文)
发布时间:2021-03-28 17:36
肠道菌群与能量代谢密切相关,其组成和代谢紊乱可通过多种途径导致胰岛素抵抗、肥胖和2型糖尿病.黄连素因具有减重、降糖、调脂等作用被广泛用于肥胖、2型糖尿病及非酒精性脂肪性肝病等代谢性疾病的辅助治疗.研究表明,黄连素可调节肠道菌群的组成和代谢,改善肠道微生态环境,从而改善胰岛素抵抗和代谢.本文综述了黄连素通过肠道菌群-炎症轴在干预代谢性疾病的研究进展,以期为代谢性疾病的治疗寻找新的策略,并为今后该领域的深入研究提供指导意义.
【文章来源】:生物化学与生物物理进展. 2020,47(08)北大核心SCICSCD
【文章页数】:9 页
【文章目录】:
1 Gut microbiota and metabolic diseases
1.1 Gut microbiota and endotoxemia,low-grade inflammation
1.2 Gut microbiota and SCFAs
1.3 Gut microbiota and BAs
1.4 Gut microbiota and branched chain amino acids(BCAAs)
2 Treatment of metabolic diseases with berberine via the gut microbiotainflammation pathway
2.1 Obesity
2.2 T2DM
2.3 NAFLD
2.4 Atherosclerosis
3 Perspectives
【参考文献】:
期刊论文
[1]D-ribose increases triglyceride via upregulation of DGAT in the liver[J]. Yao Chen,Lexiang Yu,Yan Wei,Yang Long,Yong Xu,Tao He,Rongqiao He. Science China(Life Sciences). 2019(06)
[2]Herbal decoctosome is a novel form of medicine[J]. Xiaoyun Li,Zhu Liang,Jianchao Du,Zhiqing Wang,Song Mei,Zhiqing Li,Yan Zhao,DANDan Zhao,Yiming Ma,Jun Ye,Jiantao Xu,Yu Zhao,Jiahui Chang,Yuhao Qin,Lanlan Yu,Chenxuan Wang,Chengyu Jiang. Science China(Life Sciences). 2019(03)
本文编号:3105967
【文章来源】:生物化学与生物物理进展. 2020,47(08)北大核心SCICSCD
【文章页数】:9 页
【文章目录】:
1 Gut microbiota and metabolic diseases
1.1 Gut microbiota and endotoxemia,low-grade inflammation
1.2 Gut microbiota and SCFAs
1.3 Gut microbiota and BAs
1.4 Gut microbiota and branched chain amino acids(BCAAs)
2 Treatment of metabolic diseases with berberine via the gut microbiotainflammation pathway
2.1 Obesity
2.2 T2DM
2.3 NAFLD
2.4 Atherosclerosis
3 Perspectives
【参考文献】:
期刊论文
[1]D-ribose increases triglyceride via upregulation of DGAT in the liver[J]. Yao Chen,Lexiang Yu,Yan Wei,Yang Long,Yong Xu,Tao He,Rongqiao He. Science China(Life Sciences). 2019(06)
[2]Herbal decoctosome is a novel form of medicine[J]. Xiaoyun Li,Zhu Liang,Jianchao Du,Zhiqing Wang,Song Mei,Zhiqing Li,Yan Zhao,DANDan Zhao,Yiming Ma,Jun Ye,Jiantao Xu,Yu Zhao,Jiahui Chang,Yuhao Qin,Lanlan Yu,Chenxuan Wang,Chengyu Jiang. Science China(Life Sciences). 2019(03)
本文编号:3105967
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