微针滚轮联合外用药物治疗黄褐斑27例临床观察

发布时间：2018-02-03 19:30

本文关键词： 黄褐斑微针滚轮术维生素C 类人胶原蛋白修复敷料氢醌乳膏　出处：《中国皮肤性病学杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的探讨微针滚轮联合外用药物治疗黄褐斑的临床疗效和安全性。方法 51例黄褐斑患者随机分为两组,治疗组27例,接受微针滚轮治疗,并湿敷维生素C,然后外涂类人胶原蛋白修复敷料及氢醌乳膏;对照组24例,单纯外用类人胶原蛋白修复敷料及氢醌乳膏治疗,观察疗效及不良反应。结果治疗结束后,治疗组MASI评分8.38±0.88,有效率51.85%;对照组MASI评分14.94±2.09,有效率20.83%,差异均有统计学意义(均P0.05),但是治疗组患者满意率(77.78%)和对照组患者满意率(54.17%)差异无统计学意义(P0.05),且两组患者均未见严重不良反应。结论微针滚轮联合维生素C、类人胶原蛋白以及氢醌乳膏可提高黄褐斑疗效,且不良反应小。
[Abstract]:Objective to investigate the clinical efficacy and safety of microneedle roller combined with external medicine in the treatment of chloasma. Methods 51 patients with chloasma were randomly divided into two groups: treatment group (n = 27). After wet application of vitamin C, then coated with human collagen repair dressing and hydroquinone cream, 24 cases of control group were treated with simple external application of human collagen repair dressing and hydroquinone cream, the curative effect and adverse reaction were observed. The MASI score of the treatment group was 8.38 卤0.88, the effective rate was 51.85, the MASI score of the control group was 14.94 卤2.09, the effective rate was 20.83, the difference was statistically significant (all P 0.05, but the satisfaction rate of the treatment group was 77.78%) and the satisfaction rate of the control group was 54.17%. Conclusion Micro-needle roller combined with vitamin C, human collagen and hydroquinone cream can improve the curative effect of chloasma. And the adverse reaction is small.
【作者单位】：西安交通大学第一附属医院皮肤科;
【基金】：基金项目:西安交通大学校级新技术(2015,101)
【分类号】：R758.42
【正文快照】： 黄褐斑是面部常见且难治的影响美容的色素性皮肤病之诊,诊断标准参照中国黄褐斑治疗专家共识[2]。按患者就诊顺一,多见于育龄期妇女。临床治疗方法众多,常规治疗方法的序编号用随机数字法随机分为治疗组27例,对照组24例,治疗疗效不满意[1]。为进一步探讨最佳治疗方案,2014年10

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