青海地区银屑病患者血浆中内皮素与精神因素及病情严重程度的相关性研究

发布时间：2018-02-17 06:20

  本文关键词： 银屑病 内皮素 精神因素 青海地区　出处：《临床皮肤科杂志》2016年03期 　论文类型：期刊论文

【摘要】：正2010年流行病学调查研究显示,我国银屑病患病率为0.47%[1],全国银屑病患者已逾300万[2]。国外学者曾报告1例因在战争中经历悲痛而于6个月后发病的银屑病患者,认为其精神心理上的抑郁为本病的诱发因素[3]。内皮素(ET)是迄今发现的最强的长效缩血管活性物质,精神紧张、组织缺氧、机体氧化代谢增强及儿茶酚胺水平增高等均可刺激前内皮素原的转录,促进ET的合成和释放,其作用时间持久,不为受体及5-羟
[Abstract]:Epidemiological investigation in 2010 showed that the prevalence rate of psoriasis in China was 0.47%, and the number of psoriasis patients in China had exceeded 3 million. Foreign scholars reported a patient with psoriasis who had developed after 6 months because of his grief in the war. It is considered that depression in mental and psychological state is the predisposing factor of this disease [3] .Endothelin et is the strongest long-acting vasoconstrictive active substance found so far. The enhancement of oxidative metabolism and the increase of catecholamine level can stimulate the transcription of proendothelin and promote the synthesis and release of et.
【作者单位】： 青岛市第三人民医院皮肤科;青海大学附属医院皮肤科;
【分类号】：R758.63
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本文编号：1517421