康复新液联合强脉冲光治疗玫瑰痤疮的临床观察

发布时间：2018-03-05 13:27

本文选题：康复新液　切入点：强脉冲光　出处：《中国药房》2017年17期 　论文类型：期刊论文

【摘要】：目的:观察康复新液联合强脉冲光治疗玫瑰痤疮的效果及安全性。方法:选取我院2014年5月-2016年6月就诊的玫瑰痤疮患者50例,采用随机数字表法分为对照组和观察组,各25例。在口服甲硝唑片的基础上,对照组患者采用强脉冲光治疗;观察组患者在对照组基础上联用康复新液,采用4~6层纱布浸透药液后局部湿敷,每次5~10 min,qn。两组患者均连续治疗4周。比较两组患者的临床疗效,治疗前后的症状积分和皮肤病生活质量量表(DLQI)评分,并记录不良反应发生情况。结果:观察组患者治疗有效率为92.0%,显著高于对照组的64.0%,差异有统计学意义(P0.05)。治疗前,两组患者红斑、丘疹脓疱、瘙痒、毛细血管扩张评分及总积分和DLQI评分比较,差异均无统计学意义(P0.05);治疗后,两组患者上述评分均较治疗前显著降低,且观察组显著低于对照组,差异均有统计学意义(P0.05)。观察组不良反应发生率为16.0%,显著低于对照组的40.0%,差异有统计学意义(P0.05)。结论:康复新液联合强脉冲光治疗玫瑰痤疮效果显著,可有效改善患者红斑、丘疹脓疱、瘙痒、毛细血管扩张等症状,提高患者生活质量,且安全性较高。
[Abstract]:Objective: to observe the efficacy and safety of Kangxinye combined with intense pulse light in the treatment of roseacne. Methods: 50 patients with roseacne from May 2014 to June 2016 in our hospital were randomly divided into two groups: control group and observation group. 25 cases each. On the basis of oral metronidazole tablets, the patients in the control group were treated with intense pulse light, while the patients in the observation group were treated with the new rehabilitation solution on the basis of the control group. The patients in the two groups were treated continuously for 4 weeks. The clinical efficacy, symptom score and DLQI score before and after treatment were compared between the two groups. Results: the effective rate of treatment in the observation group was 92.0, which was significantly higher than that in the control group (64.0). The difference was statistically significant (P 0.05). Before treatment, the patients in the two groups had erythema, papules pustules, pruritus. There was no significant difference in capillary dilatation score, total score and DLQI score between the two groups after treatment, the above scores in both groups were significantly lower than those before treatment, and those in the observation group were significantly lower than those in the control group. The incidence of adverse reactions in the observation group was 16.0, which was significantly lower than that in the control group (40.05%). Conclusion: the curative effect of Kangfeng Xin liquid combined with strong pulse light on acne rosacea is significant and can effectively improve the erythema of the patients. Papules pustules, pruritus, capillary dilatation and other symptoms, improve the quality of life of patients, and high safety.
【作者单位】：河北医科大学第四医院皮肤科;河北医科大学第四医院肿瘤内科;河北医科大学第四医院中医科;
【分类号】：R758.734

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