寻常型银屑病患者血液学指标变化及临床意义

发布时间：2018-03-08 23:21

  本文选题：寻常型银屑病　切入点：NLR　出处：《实用医学杂志》2017年24期 　论文类型：期刊论文

【摘要】：目的探讨寻常型银屑病患者血液中相关指标变化特点及其在临床中的意义。方法收集38例通过临床及组织病理诊断明确的寻常型银屑病患者,并对其进行疾病严重程度评分(PASI),及40例健康体检者血中性粒细胞/淋巴细胞比值(NLR)、C-反应蛋白(CRP)、总胆固醇、甘油三酯、血尿酸值,比较两组中上述指标,并采用Pearson相关性分析PASI评分与CRP、NLR、血脂、血尿酸间的关系。结果寻常型银屑病患者NLR、总胆固醇、甘油三酯、血尿酸均明显高于对照组(P0.05)。PASI评分与NLR间呈正相关(P0.05),CRP与NLR及PASI评分与CRP间无相关性(P0.05)。PASI评分≥7分的患者,其血尿酸水平比7分者更高。结论 NLR能反映寻常型银屑病患者病情及系统炎症状态,病情越重者血尿酸水平越高。
[Abstract]:Objective to investigate the changes of blood parameters in psoriasis vulgaris and its clinical significance. Methods 38 patients with psoriasis vulgaris diagnosed by clinical and histopathological diagnosis were collected. The serum neutrophil / lymphocyte ratio, total cholesterol, triglyceride and serum uric acid were compared between the two groups, and the serum neutrophil / lymphocyte ratio of 40 healthy controls were compared. The serum neutrophil / lymphocyte ratio was compared between the two groups, and the total cholesterol (TC), triglyceride (TG) and serum uric acid (SA) were compared between the two groups. Pearson correlation analysis was used to analyze the relationship between PASI score, serum lipid, serum uric acid and PASI score in patients with psoriasis vulgaris. Serum uric acid was significantly higher than that in control group (P 0.05U. PASI and NLR). There was a positive correlation between serum uric acid and NLR and no correlation between PASI score and CRP. PASI score 鈮，

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