透明胶带粘贴皮疹区脱落细胞法鉴别点滴状银屑病与玫瑰糠疹

发布时间：2018-03-16 07:34

本文选题：透明胶带　切入点：脱落细胞　出处：《中国皮肤性病学杂志》2017年10期 　论文类型：期刊论文

【摘要】：目的探索用透明胶带粘贴表层脱落细胞法鉴别不典型点滴状银屑病与玫瑰糠疹的可行性。方法对因临床表现不典型,通过组织病理诊断为点滴状银屑病患者和玫瑰糠疹,用透明胶带粘贴皮疹区表层,采集脱落细胞进行苏木素伊红(HE)染色和免疫组织化学染色。中性粒细胞群集为阳性结果,诊断为点滴状银屑病;中性粒细胞散在分布或无中性粒分布为阴性结果,诊断为玫瑰糠疹。将两组患者的诊断率进行比较。结果银屑病组患者标本中性粒细胞群集分布率为93.33%(28/30)、散在分布率为6.67%(2/30)、无分布为0。而玫瑰糠疹组标本的中性粒细胞群聚分布率为0、散在分布率为10.00%(3/30),无分布为90.00%(27/30),两组患者的中性细胞群聚分布率与非群聚分布率差异有统计学意义(P0.01)。透明胶带法对点滴状银屑病和玫瑰糠疹的诊断符合率分别为93.33%和100.00%,总诊断准确率为96.67%。结论透明胶带粘贴脱落细胞HE染色法操作简便易行,患者依从性高,是鉴别不典型点滴状银屑病与玫瑰糠疹的实验诊断方法之一。
[Abstract]:Objective to explore the feasibility of differentiating atypical psoriasis and pityriasis roseus by the method of transparent adhesive tape sticking surface exfoliated cells. Methods the patients with psoriasis and pityriasis roseus were diagnosed by histopathology because of atypical clinical manifestations. The exfoliated cells were stained by hematoxylin eosin (HEH) and immunohistochemical staining. The neutrophils were positive and diagnosed as droplet psoriasis. The distribution of neutrophils in or without neutrophils was negative. The diagnostic rate of pityriasis roseus was compared between the two groups. Results the neutrophil cluster distribution rate of psoriasis group was 93.33 / 30%, the scattered distribution rate was 6.67% / 30%, and none was 0%. The distribution rate of neutrophils was 0, the distribution rate was 10.00% / 30%, and the distribution rate was 90.0010 / 30%. There was a significant difference between the neutrophil cluster distribution rate and the non-cluster distribution rate in the two groups. The diagnostic signs of psoriasis and pityriasis roseus were detected by transparent tape method. The total diagnostic accuracy was 96.677.Conclusion it is easy to use HE staining method of adhesive tape in exfoliated cells, and the total diagnostic accuracy is 96.677.Conclusion it is easy to use HE staining method to paste exfoliated cells with transparent tape. Patients with high compliance are one of the experimental diagnostic methods for distinguishing atypical psoriasis from pityriasis roseus.
【作者单位】：浦东新区周浦医院皮肤科;
【分类号】：R758.6

【相似文献】