加味土槐饮联合中波高能紫外线照射治疗寻常型斑块状银屑病的临床观察

发布时间：2018-03-19 15:23

本文选题：寻常型斑块状银屑病　切入点：加味土槐饮　出处：《南京中医药大学》2010年硕士论文　论文类型：学位论文

【摘要】： 目的：评价加味土槐饮联合中波高能紫外线照射治疗寻常型斑块状银屑病的临床疗效。方法：55例患者随机分为3组：中药组(18例),单照光组(17例),联合组(20例)。中药组口服加味土槐饮,每日2次；单照光组每周照射2次中波高能紫外线；联合组口服加味土槐饮,每日2次,并且每周照射2次中波高能紫外线。疗程均为4周,分别在治疗前,治疗1周后、2周后、3周后、4周后进行ESI评分,观察疗效。结果：治疗4周后三组ESI积分均显著下降(P0.05)；治疗4周后疗效指数比较,联合组优于中药组(P=0.0000.05),单照光组优于中药组(P=0.0000.05),联合组优于单照光组(P=0.0280.05)。治疗4周后三组有效率比较,中药组与单照光组比较(P=0.270.0167),差异无统计学意义；单照光组与联合组比较(P=0.6990.0167),差异无统计学意义；中药组与联合组比较(P=0.0080.0167),差异有统计学意义,联合组有效率大于中药组有效率。结论：加味土槐饮和中波高能紫外线治疗寻常型斑块状银屑病均具有较好的疗效,两者联合治疗疗效优于单独治疗,两者疗效存在叠加效果。
[Abstract]:Objective: to evaluate the clinical effect of Jiawei Tuhuai decoction combined with high energy ultraviolet irradiation on plaque psoriasis vulgaris. Methods Fifty-five patients were randomly divided into three groups: Chinese medicine group (n = 18), single light group (n = 17) and combined group (n = 20). The combined group was treated with modified Duhuai decoction twice a day and irradiated twice a week with high energy ultraviolet B (UVB). The course of treatment was 4 weeks. The ESI score was evaluated before treatment, 2 weeks after 1 week and 3 weeks after treatment, and 4 weeks after treatment. Results: after 4 weeks of treatment, the ESI score of the three groups decreased significantly (P 0.05), and the curative effect index was compared after 4 weeks of treatment. The combined group was superior to the traditional Chinese medicine group (0.0000.05), the single light group was better than the traditional Chinese medicine group (0.0000.05), the combined group was superior to the single light group (P 0.0280.05). After 4 weeks of treatment, the effective rates of the three groups were compared, and there was no significant difference between the traditional Chinese medicine group and the single light group (0.270.0167). There was no significant difference between the single light group and the combined group, but there was no significant difference between the traditional Chinese medicine group and the combined group, the difference was statistically significant, and the effective rate of the combined group was higher than that of the traditional Chinese medicine group. Conclusion: both modified Duhuai decoction and high energy ultraviolet radiation have good therapeutic effect on plaque psoriasis vulgaris. The combined treatment effect is better than that of single treatment, and there is a superposition effect between them.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R758.63

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