泛发性光泽苔藓并发毛发扁平苔藓
发布时间:2018-03-25 04:38
本文选题:光泽苔藓 切入点:毛发扁平苔藓 出处:《临床皮肤科杂志》2014年09期
【摘要】:报告1例泛发性光泽苔藓并发毛发扁平苔藓。患儿女,4岁。头皮、颈项部、背部及四肢出现肤色丘疹4年余。皮肤科检查:头皮可见毛囊性针头大丘疹,毛发稀疏卷曲;颈项、背部及四肢可见针头大肤色坚实丘疹,有光泽。皮损组织病理检查:角化过度伴角化不全,基底细胞液化变性,真皮乳头浅层半球形浸润性细胞团块,团块两侧表皮突延长,呈典型的"抱球状"外观;同时可见毛囊上皮基底细胞液化变性,周围可见淋巴细胞为主的带状浸润。免疫组化显示浸润细胞以CD4~+细胞为主。诊断:泛发性光泽苔藓并发毛发扁平苔藓。治疗:给予他克莫司软膏,维A酸乳膏外用,转移因子口服液治疗,病情好转。
[Abstract]:A case of generalized lichen lustre complicated with hair lichen planus was reported. The child was 4 years old. Skin papules appeared on the scalp, neck, back and extremities for more than 4 years. On the back and on the extremities, the needle had a solid skin colour and a luster. Histopathological examination of the lesions: keratosis with hypokeratosis, liquefaction of basal cells, superficial hemispherical infiltrating cell mass of dermal papilla, and extension of the epidermis on both sides of the mass. Typical "clasping" appearance and liquefaction degeneration of basal cells of hair follicle epithelium can be seen at the same time. Immunohistochemical staining showed that the infiltrating cells were mainly CD4cells. Diagnosis: generalized lichen lustre complicated with hair lichen planus. Treatment: tacrolimus ointment, retinoic acid cream for external use, Transfer factor oral liquid treatment, the condition improved.
【作者单位】: 北京中日友好医院皮肤科;
【分类号】:R758.6
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