鳖甲煎丸联合西药治疗血热型寻常型银屑病的疗效观察

发布时间：2018-03-25 12:47

  本文选题：鳖甲煎丸　切入点：血热型寻常型银屑病　出处：《中成药》2017年10期

【摘要】：目的探讨鳖甲煎丸联合西药治疗血热型寻常型银屑病的疗效观察。方法 2015年1月—2016年1月,共收治128例中老年血热型寻常型银屑病患者,随机(数字随机分组法)分为两组,对照组采用西医常规疗法,观察组在西医常规疗法的基础上,采用鳖甲煎丸进行治疗。观察和比较患者的治疗效果、不良反应、免疫调节作用、PASI(皮损面积及严重性指数)评分。结果与对照组(78.13%)对比,观察组治疗有效率(98.44%)明显更高,数据差异显著,具有统计学意义(P0.05)。与治疗前对比,观察组治疗1、2、3个月的PASI分明显降低,对照组治疗2个月、3个月的PASI分明显降低,数据差异显著,具有统计学意义(P0.05)。与对照组对比,观察组治疗1、2、3个月的PASI分明显更低,数据差异显著,具有统计学意义(P0.05)。与治疗前对比,两组CD4+明显降低,CD4+/CD8+明显上升,数据比较差异具有统计学意义,P0.05;与对照组对比,两组治疗后CD4+和CD4+/CD8+比较差异不具有统计学意义(P0.05)。与对照组(20.31%)对比,观察组不良反应发生率(7.81%)明显更低,数据比较差异具有统计学意义(P0.05)。结论基于西医常规疗法鳖甲煎丸治疗血热型寻常型银屑病的疗效显著,不良反应少,能够有效地提高患者的免疫能力,安全性良好。
[Abstract]:Objective to observe the curative effect of Biejia Jian Pill combined with western medicine in treating psoriasis vulgaris of blood fever type. Methods A total of 128 cases of psoriasis vulgaris of blood fever type were treated from January 2015 to January 2016. They were randomly divided into two groups. The control group was treated with routine western medicine, while the observation group was treated with Biejia Jian Pill on the basis of western medicine routine therapy. The therapeutic effects and adverse reactions of the patients were observed and compared. Results compared with the control group (78.13), the effective rate of treatment in the observation group was significantly higher than that in the control group (P 0.05), and the difference was significant (P 0.05). The PASI score of the observation group was significantly lower than that of the control group for 2 months and the PASI score for 3 months. The difference was significant (P 0.05). Compared with the control group, the PASI score of the observation group was significantly lower than that of the control group, and the PASI score of the observation group was significantly lower than that of the control group. The difference was statistically significant (P 0.05). Compared with the control group, CD4 in the two groups decreased significantly the CD4 / CD8 ratio increased significantly, the difference was statistically significant (P0.05), and compared with the control group, there was no significant difference between the two groups. There was no significant difference in CD4 and CD4 / CD8 between the two groups after treatment. Compared with the control group (20.31), the incidence of adverse reactions in the observation group was significantly lower than that in the control group (7.81%). Conclusion Biejia Jian Pill, based on routine western medicine therapy, has significant curative effect and fewer adverse reactions in the treatment of blood-heat type psoriasis vulgaris. It can effectively improve the immune ability of the patients and has good safety.
【作者单位】： 湖北省黄石市鄂东医疗集团中医医院;
【分类号】：R758.63
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本文编号：1663198