绵阳市MSM队列研究梅毒新发感染及影响因素

发布时间：2018-04-02 20:56

  本文选题：男男性行为者　切入点：队列研究　出处：《中国公共卫生》2014年10期

【摘要】：目的了解四川省绵阳市男男性行为者(MSM)梅毒新发感染情况及影响因素。方法 2009年6—9月采用同伴推动招募法(RDS)在绵阳城区招募调查符合条件梅毒检测阴性的MSM建立开放性前瞻队列,每年随访1次,连续3年。随访中不足基线调查样本部分结合滚雪球抽查法,依据纳入条件补充调查对象。结果研究期间共纳入队列583人,随访535.5人年,梅毒阳转30例,新发感染率5.6/100人年(95%CI=3.7/100人年~7.6/100人年),近2年明显下降。多因素分析显示,婚姻状况(RR=2.377,95%CI=1.035~5.459)、艾滋病知识知晓(RR=4.278,95%CI=1.941~9.431),近1年接受过同伴教育(RR=2.281,95%CI=1.081~4.815),近6月诊断过性病(RR=4.743,95%CI=1.829~12.302)是梅毒新发感染的独立影响因素。结论绵阳市MSM人群梅毒新发感染有所下降,但感染率仍较高,受婚姻状况、艾滋病知识知晓、同伴教育和性病感染影响。
[Abstract]:Objective to investigate the incidence and influencing factors of syphilis in MSMM in Mianyang, Sichuan province.Methods from June to September 2009, Peer driven recruitment (RDS) was used to establish an open prospective cohort of syphilis negative MSM in Mianyang urban area, followed up once a year for 3 consecutive years.In the follow-up, some samples of baseline survey were combined with snowball sampling method to supplement the subjects according to the inclusion conditions.Results A total of 583 people were enrolled in the study period, and 535.5 follow-up years were followed up. 30 cases of syphilis positive turned to positive. The rate of new infection was 5.6% / 100 person / year / 95% CIQ / 100 person year or 7.6% / 100 person / year, and the last two years were obviously decreased.澶氬洜绱犲垎鏋愭樉绀，

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