Q开关Nd:YAG激光联合重组牛碱性成纤维细胞生长因子治疗寻常型痤疮

发布时间：2018-04-10 09:45

本文选题：痤疮　切入点：大光斑低能量Q开关Nd　出处：《实用医学杂志》2016年17期

【摘要】：目的:观察大光斑低能量Q开关Nd:YAG激光联合重组牛碱性成纤维细胞生长因子(b FGF)治疗寻常型痤疮的临床效果及不良反应。方法:86例痤疮患者随机分为两组,采用Q开关Nd:YAG激光治疗,1次/2周,6~8次为1个疗程。治疗组术后给予重组牛b FGF凝胶外用,1次/d;对照组仅给予激光治疗。治疗10周后观察粉刺、炎性皮损、皮肤油脂分泌情况及不良反应,并随访3~6个月。结果:治疗组总有效率为89.13%,对照组有效率为72.50%,差异有统计学意义(P0.05),其中炎性皮损的疗效治疗组明显优于对照组,差异有统计学意义(t=2.169,P0.05)。结论:大光斑低能量Q开关Nd:YAG激光联合重组牛b FGF对寻常型痤疮治疗有效,对炎性皮损疗效更佳,且无明显不良反应。
[Abstract]:Objective: to observe the clinical effect and adverse reaction of large spot low energy Q switch Nd:YAG laser combined with recombinant bovine basic fibroblast growth factor (BbFGF) in the treatment of acne vulgaris.Methods Eighty-six patients with acne were randomly divided into two groups. The patients were treated with Q-switched Nd:YAG laser for 6 times per second week for 8 times as a course of treatment.The treatment group was treated with recombinant bovine b FGF gel 1 / d after operation, while the control group was only treated with laser.After 10 weeks of treatment, acne, inflammatory lesions, skin fat secretion and adverse reactions were observed and followed up for 3 ~ 6 months.Results: the total effective rate was 89.13 in the treatment group and 72.50 in the control group. The difference was statistically significant (P 0.05). The therapeutic effect of inflammatory lesions in the treatment group was significantly better than that in the control group, and the difference was statistically significant.Conclusion: large spot and low energy Q switch Nd:YAG laser combined with recombinant bovine b FGF is effective in the treatment of acne vulgaris, and has no obvious adverse effects on inflammatory lesions.
【作者单位】：大理大学临床医学院医学美容教研室;
【分类号】：R758.733

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