418例基底细胞癌病例临床病理特点回顾分析

发布时间：2018-04-16 17:23

本文选题：皮肤肿瘤 + 肿瘤　；参考：《北京大学学报(医学版)》2014年02期

【摘要】：目的:探讨中国人群基底细胞癌临床和病理特征。方法:回顾基底细胞癌病例的临床及病理资料并进行统计分析。结果:共收集418个病例,男女比例为0.77∶1,平均年龄(65.39±13.51)岁。年龄小于60岁的病例占29%,其中男女比例为1.16∶1。分析病理亚型,结节型占81.8%,其次是浅表型(9.8%),剩余病理亚型所占比例小于10%。头面部肿瘤发生最多(86.6%),硬斑病样型全部分布于头面部,多数结节型也位于头面部,其他亚型常见于躯干和四肢。86.6%肿瘤有色素沉着,80.4%无溃疡表现。比较临床与病理诊断符合率,头面(84.7%)和躯干(79.1%)均高于四肢(46.2%)。结论:多数临床病理特征与高加索人群相似,值得关注和研究的特点有:中青年患者占有相当比例,该人群性别比例与老年人群不同;多数肿瘤有色素沉着,但溃疡发生率较低;多发基底细胞癌病例较少;皮脂腺痣并发基底细胞癌的患者年龄较大。临床与病理诊断符合率的研究提示无论从医生角度还是患者角度,都应加强对基底细胞癌的关注。
[Abstract]:Objective: to investigate the clinical and pathological features of basal cell carcinoma (BCC) in Chinese population.Methods: the clinical and pathological data of patients with basal cell carcinoma were reviewed and analyzed statistically.Results: a total of 418 cases were collected. The ratio of male to female was 0.77: 1, with an average age of 65.39 卤13.51 years.The number of cases under the age of 60 is 29, of which the ratio of men to women is 1. 16: 1.In the analysis of pathological subtypes, nodular type accounted for 81.8%, followed by superficial type (9.8%), and the remaining pathological subtype accounted for less than 10%.Most of the tumors occurred in the head and face with 86.6% of the tumors, and most of the nodular types were found in the head and face. Other subtypes were found in the trunk and limbs. 86.6% of the tumors had hyperpigmentation and 80.4% of the tumors had no ulcers.The coincidence rate of clinical diagnosis and pathological diagnosis was higher than that of 46.2% of the quadrilateral gyrus (84.74.7g) and the trunk (79.1%).Conclusion: the majority of clinicopathological features are similar to those of Caucasian population, and the characteristics worthy of attention and study are as follows: the proportion of young and middle-aged patients is quite high, the sex ratio of this population is different from that of the elderly, and most tumors have pigmentation.But the incidence of ulcers was lower, the cases of multiple basal cell carcinoma were less, and the patients with sebaceous nevus complicated with basal cell carcinoma were older.The study of coincidence rate between clinical and pathological diagnosis suggests that attention should be paid to basal cell carcinoma both from the doctor's point of view and from the patient's point of view.
【作者单位】：北京大学第一医院皮肤科;郑州市中心医院皮肤科;北京大学第一医院医学统计室;
【基金】：北京市优秀人才培养基金(2010D009001000002)资助~~
【分类号】：R739.5

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