孕妇慢性荨麻疹中医辨证联合葡萄糖酸钙进行治疗的安全性及疗效探讨

发布时间：2018-04-18 12:26

本文选题：中医辨证 + 葡萄糖酸钙　；参考：《中国妇幼保健》2014年23期

【摘要】：目的:探讨中医辨证联合葡萄糖酸钙治疗孕妇慢性荨麻疹的疗效及安全性。方法:选取该院2012年1月~2013年12月门诊就诊的孕妇慢性荨麻疹患者共120例,随机分为实验组和对照组,对照组予以葡萄糖酸钙常规治疗,实验组在葡萄糖酸钙的基础上,加用中医辨证治疗。对比两组患者治疗前及治疗2周后的治疗前后各项症状、体征评分和总积分,IL-2、IL-4水平和治疗2周后的近期疗效。结果:两组患者治疗2周后的各项症状、体征评分显著低于治疗前,P0.01;实验组治疗2周后的各项症状、体征评分显著低于对照组,P0.01。两组患者治疗2周后的IL-4水平显著低于治疗前,IL-2水平显著高于治疗前,P0.01;实验组治疗2周后的IL-4水平显著低于治疗前,IL-2水平显著高于对照组,P0.01。实验组治疗2周后的总有效率显著高于对照组,χ2=7.884 9,P0.01。两组患者治疗后均无显著不良反应。结论:中医辨证联合葡萄糖酸钙治疗孕妇慢性荨麻疹临床疗效优于单用葡萄糖酸钙且安全、可靠。
[Abstract]:Objective: to explore the efficacy and safety of TCM combined with calcium gluconate in the treatment of pregnant women with chronic urticaria.Methods: 120 pregnant women with chronic urticaria from January 2012 to December 2013 were randomly divided into experimental group and control group. The control group was treated with calcium gluconate, and the experimental group was treated with calcium gluconate.Add treatment with TCM syndrome differentiation.The symptoms, signs and total score of IL-2 / IL-4 before and after 2 weeks treatment were compared between the two groups.Results: the scores of symptoms and signs in the two groups were significantly lower than those in the control group after 2 weeks of treatment (P 0.01), and the scores of symptoms and signs in the experimental group were significantly lower than those in the control group (P 0.01) after 2 weeks of treatment.After 2 weeks of treatment, the level of IL-4 in both groups was significantly lower than that before treatment (P 0.01), and the level of IL-4 in experimental group was significantly lower than that in control group (P 0.01) 2 weeks after treatment.The total effective rate of the experimental group after 2 weeks treatment was significantly higher than that of the control group (蠂 2 = 7.8849, P 0.01).There was no significant adverse reaction after treatment in both groups.Conclusion: the clinical efficacy of TCM combined with calcium gluconate in the treatment of pregnant women with chronic urticaria is better than that of calcium gluconate alone.
【作者单位】：武警江苏总队南京医院皮肤科;解放军81医院皮肤科;武警江苏省总队医院;
【分类号】：R714.25;R758.24

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