1550nm铒玻璃点阵激光治疗炎症性痤疮16例临床观察

发布时间：2018-05-09 15:47

本文选题：痤疮 + nm　；参考：《中国皮肤性病学杂志》2014年09期

【摘要】：目的评估1 550nm铒玻璃点阵激光治疗中重度痤疮的临床疗效和安全性。方法采用1 550nm铒玻璃点阵激光治疗16例中重度痤疮患者。使用点阵密度169点/cm2,能量密度10mJ/cm2,首先对活动性皮损照射一遍,然后对整个面部照射一遍,共治疗4次,每次间隔2周。治疗结束后6个月时再抽取其中8例患者进行对照研究,仅对其中有4例接受1次附加治疗,3个月后进行最终疗效评估。结果有13例患者完成了治疗和随访。治疗结束后6个月时患者评价Burton痤疮评分的平均改善率为68.12%,观察者为81.36%,未使用麻醉药物,未出现不良反应。接受附加1次治疗后的3个月时,接受1次附加治疗组患者评价Burton痤疮评分的平均改善率为80.65%,观察者为84.37%,明显高于未接受附加治疗的患者(68.04%和75.31%),前者明显优于后者,差异均有统计学意义(P均0.05)。结论 1 550nm铒玻璃点阵激光治疗面部炎性痤疮疗效好,疼痛轻微且无不良反应,增加其维持治疗次数可提高临床疗效。
[Abstract]:Objective to evaluate the efficacy and safety of 1 550nm erbium glass lattice laser in the treatment of moderate and severe acne. Methods 16 patients with moderate and severe acne were treated with 1 550nm erbium glass lattice laser. Using a lattice density of 169 points / cm ~ (2) and an energy density of 10 mg / cm ~ (2), the active skin lesions were first irradiated once, then the whole face was irradiated once, for a total of four times, at intervals of 2 weeks. After 6 months of treatment, 8 of them were selected for a control study, only 4 of them received one additional treatment, and 3 months later the final outcome was evaluated. Results 13 patients completed treatment and follow-up. At 6 months after treatment, the average improvement rate of Burton acne score was 68.12 and 81.36 in the observer. No anesthesia was used and no adverse reactions were observed. The average improvement rate of Burton acne score was 80.65, 84.37 in the observer group and 68.04% in the patients without additional treatment and 75.31% in the treatment group, which was significantly better than that in the latter group, 3 months after the first treatment, and the average improvement rate of acne score was 80.65, 84.37 in the observer group, and 75.31% in the control group. The difference was statistically significant (P < 0.05). Conclusion 1 the treatment of facial inflammatory acne by 550nm erbium glass lattice laser is effective, the pain is mild and there is no adverse reaction. Increasing the frequency of maintenance therapy can improve the clinical efficacy.
【作者单位】：西安交通大学医学院第二附属医院皮肤科;
【基金】：国家自然科学基金(30901298)
【分类号】：R758.733

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