昆明山海棠递减疗法治疗激素依赖性皮炎34例临床观察

发布时间：2018-05-11 21:13

本文选题：激素依赖性皮炎 + 昆明山海棠　；参考：《中国皮肤性病学杂志》2014年02期

【摘要】：目的观察昆明山海棠片递减疗法治疗激素依赖性皮炎的临床疗效和安全性。方法将入选的68例患者随机分为两组,治疗组(34例):口服昆明山海棠片4片,3次/d,每间隔2周减量;对照组(34例):外搽0.1%丁酸氢化可的松乳膏,2次/d,治疗2周后改为1次/d,治疗第6周末时改为隔天1次外搽;同时两组患者均口服地氯雷他定片5mg,1次/d,疗程均为8周。治疗期间每2周随访1次,至停药后2周时。结果 68例患者中有62例完成临床试验,治疗组有效率75.00%,对照组为83.33%,差异无统计学意义(P0.05)。治疗组平均起效时间为(21.2士6.5)d,对照组为(16.5±5.1)d;停药后2周时,治疗组复发率37.50%,对照组为68.00%;以上差异均有统计学意义(P均0.05)。且治疗组未见明显不良反应。结论昆明山海棠递减疗法治疗激素依赖性皮炎安全而有效,可明显降低该病的复发率。
[Abstract]:Objective to observe the clinical efficacy and safety of decreasing therapy for hormone dependent dermatitis. Methods Sixty-eight patients were randomly divided into two groups. 34 patients in the treatment group were divided into two groups. In the control group, 34 cases were treated with 0.1% hydrocortisone butyrate cream twice a day, once a day after 2 weeks of treatment and once every other day at the end of the 6th week, and at the same time, the patients in both groups were given desloratadine 5 mg / d for 8 weeks. The patients were followed up every 2 weeks until 2 weeks after withdrawal. Results Sixty-two of 68 patients completed the clinical trial. The effective rate was 75.00 in the treatment group and 83.33 in the control group. The difference was not statistically significant (P 0.05). The average effective time was 21.2 卤6.5 days in the treatment group and 16.5 卤5.1 days in the control group, and the recurrence rate was 37.50 in the treatment group and 68.00 in the control group at 2 weeks after the treatment. There was no obvious adverse reaction in the treatment group. Conclusion it is safe and effective to treat hormone dependent dermatitis with decrement therapy of Tripterygium hypoglaucum, and can obviously reduce the recurrence rate of the disease.
【作者单位】：成都中医药大学医学技术学院;成都中医药大学第二附属医院皮肤科;成都中医药大学基础医学院;
【分类号】：R758.25

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