5%咪喹莫特乳膏治疗儿童寻常疣39例临床观察

发布时间：2018-05-13 08:01

本文选题：寻常疣 + 咪喹莫特　；参考：《中国皮肤性病学杂志》2017年09期

【摘要】：目的评价5%咪喹莫特乳膏治疗儿童寻常疣的临床疗效和安全性。方法将入选的86例寻常疣患儿按照随机数字表分成两组。治疗组(39例)每晚睡前予5%咪喹莫特乳膏外搽,6~10h后清洗患处皮肤,每周连续用5d,停用2d为1个疗程。对照组(47例)予液氮冷冻治疗。两组患者疗程均为12周。结果治疗12周后,治疗组有效率为64.10%,对照组有效率为80.85%,差异无统计学意义(P0.05)。治疗过程中,治疗组不良反应发生率为25.64%,对照组不良反应发生率为89.36%,差异有统计学意义(P0.01)。治疗组复发率为8.00%,对照组复发率为26.32%,差异无统计学意义(P0.05)。结论 5%咪喹莫特乳膏治疗儿童寻常疣安全有效,不良反应少。
[Abstract]:Objective to evaluate the efficacy and safety of 5% Imiquimod cream in the treatment of children with verruca vulgaris. Methods 86 children with verruca vulgaris were randomly divided into two groups. The treatment group (39 cases) were given 5% imiquimod ointment for 10 hours before bedtime. The skin of affected area was cleaned for 5 days every week, and stopped for 2 days as a course of treatment. The control group (n = 47) was treated with liquid nitrogen cryotherapy. The course of treatment was 12 weeks. Results after 12 weeks of treatment, the effective rate was 64.10 in the treatment group and 80.85 in the control group. The difference was not statistically significant (P 0.05). In the course of treatment, the incidence of adverse reactions in the treatment group was 25.64 and that in the control group was 89.36. The difference was statistically significant (P 0.01). The recurrence rate was 8.00 in the treatment group and 26.32 in the control group. The difference was not statistically significant (P 0.05). Conclusion 5% Imiquimod cream is safe and effective in the treatment of children with verruca vulgaris.
【作者单位】：温州医科大学附属第三医院皮肤科;
【基金】：温州市科技局立项课题(Y20150279)
【分类号】：R752.51

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