雄激素性秃发患者家族遗传史的临床分析研究

发布时间：2018-05-18 09:53

本文选题：雄激素性秃发 + 改良BASP分类分级法　；参考：《临床皮肤科杂志》2015年12期

【摘要】：目的:利用改良的basic and specific(BASP)分类分级法探讨雄激素性秃发(AGA)家族遗传史与其秃发类型、发病年龄、秃发严重程度及疗效的关系。方法:收集2013年1月—2014年12月来南京医科大学第一附属医院皮肤科毛发疾病门诊就诊的AGA患者。根据患者脱发情况进行改良的BASP分型,按照其脱发家族史进行分组,利用统计软件SPSS 22.0进行分析。结果:男性AGA患者家族史阳性率明显高于女性。AGA患者的基本秃发类型在父子间具有相关性。有AGA家族史的男性患者比无家族史患者在相同发病时间内脱发更严重,而女性患者脱发严重程度受家族史影响小。有AGA家族史患者平均发病年龄比无家族史患者早。AGA家族史对于治疗脱发疗效无影响。结论:有AGA家族史患者发病年龄早,脱发严重程度加重,且不同族系、不同亲缘级别的家族史对于患者脱发类型、严重程度的影响也不同,不同性别的患者受家族史的影响也有差别。
[Abstract]:Objective: to investigate the relationship between the genetic history of androgen alopecia areata (AGA) and its type, onset age, severity of alopecia and curative effect by using the improved basic and specific basic classification method. Methods: from January 2013 to December 2014, AGA patients from the Department of Dermatology, Department of Dermatology, first affiliated Hospital of Nanjing Medical University were collected. According to the patients' alopecia, the improved BASP classification was carried out. According to their family history of alopecia, the SPSS 22.0 was used to analyze it. Results: the positive rate of family history in male patients with AGA was significantly higher than that in females. The male patients with AGA family history had more severe hair loss than those with no family history, while the female patients were less affected by the family history. The average onset age of patients with AGA family history was earlier than that of patients without family history. Conclusion: the patients with AGA family history have earlier onset age, more severe alopecia, and different family history of different families and different relative levels have different influence on the type and severity of hair loss. Patients of different genders are also affected by family history.
【作者单位】：南京医科大学第一附属医院皮肤性病科;
【分类号】：R758.71

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