CT引导下经皮穿刺胸腔入路内脏大小神经阻滞术治疗胰腺癌疼痛的疗效研究

发布时间：2018-06-04 05:23

本文选题：内脏大小神经 + 阻滞　；参考：《中国疼痛医学杂志》2014年05期

【摘要】：目的:研究CT引导下经皮穿刺胸腔入路内脏大小神经阻滞术治疗胰腺癌疼痛的临床疗效。方法:选择胰腺癌晚期上腹部或腰背部顽固性疼痛患者42例,在CT引导下经胸腔入路双针穿刺,行无水乙醇阻滞内脏大小神经。观察有无各种并发症;观察并随访术前、术后1周、1个月、3个月患者的疼痛视觉模拟评分(visual analogue pain scale,VAS)随访并评定疗效、生活质量(quality of life,QOL)评分及口服吗啡日用量。结果:无一例发生严重并发症;术后1周临床治愈36例,显效6例;与术前比较,术后各时间点的VAS评分及吗啡日用量均较术前显著降低(P0.05),而术后各时间点QOL评分则显著升高(P0.05)。结论:CT引导下经皮穿刺胸腔入路内脏大小神经阻滞术治疗胰腺癌顽固性疼痛疗效好、安全性高、简单易行,并显著提高患者的生活质量。
[Abstract]:Objective: to study the clinical effect of CT-guided percutaneous thoracotomy and visceral nerve block in the treatment of pancreatic cancer pain. Methods: Forty-two patients with intractable pain in the upper abdomen or lower back of advanced pancreatic cancer were selected. Under the guidance of CT, the visceral and small nerves were blocked by anhydrous alcohol. All kinds of complications were observed and followed up before operation, 1 week, 1 month and 3 months after operation. Visual analogue pain scale (VAS) was followed up to evaluate the efficacy, quality of life (QOL) score and daily dose of morphine. Results: no serious complications occurred, 36 cases were cured 1 week after operation, 6 cases were significantly improved. Compared with preoperative, the VAS score and daily dose of morphine at each time point after operation were significantly lower than those before operation (P 0.05), but the QOL score at each time point after operation was significantly higher than that before operation (P 0.05). Conclusion Percutaneous thoracotomy with small and small visceral nerve block under the guidance of CT is effective, safe, simple and effective in the treatment of intractable pain of pancreatic cancer. It also improves the quality of life of the patients.
【作者单位】：宁波大学医学院附属李惠利医院疼痛科;南昌大学第一附属医院疼痛科;
【分类号】：R739.5

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