曲安奈德穴位注射联合中药皮肤康洗液治疗肛门湿疹的临床研究

发布时间：2018-06-05 07:45

本文选题：曲安奈德 + 穴位注射　；参考：《辽宁中医杂志》2017年06期

【摘要】：目的:探讨曲安奈德穴位注射联合中药皮肤康洗液在肛门湿疹临床治疗中的应用价值。方法:选取2013年3月—2015年12月于本院就诊的124例肛门湿疹湿热证患者为受试对象,随机数字表法分为研究组和对照组各62例。对照组中途脱落4例,共58例有效病例入组;研究组中途脱落6例,共56例有效病例入组。对照组:温水坐浴+糠酸莫米松乳膏外涂方案。研究组:曲安奈德穴位注射联合中药皮肤康洗液外洗方案。对比两组受试者临床疗效及不良反应发生率差异,记录其治疗前后相关指标[血清白细胞介素-2(IL-2)、白细胞介素-4(IL-4)、白细胞介素-6(IL-6)和胃泌素(Gas)]检测结果、皮损最大直径及症状(瘙痒、灼热、疼痛、大便秘结、小便短赤、口干心烦)积分变化情况。结果:研究组治疗总有效率显著高于对照组(91.1%vs 72.4%,P0.05)。治疗2周后,两组受试者血清IL-2水平均较治疗前显著提升,且研究组对照组;部分指标(血清IL-4、IL-6、Gas)检测水平、皮损最大直径检测结果及症状积分评估结果则较治疗前显著降低,且研究组对照组,差异均有统计学意义(P0.05)。研究组治疗后出现月经紊乱、头晕、恶心症状各1例,对照组出现局部烧灼感1例,两组不良反应发生率比较,差异无统计学意义(P0.05)。结论:对肛门湿疹患者予以曲安奈德穴位注射联合中药皮肤康洗液坐浴治疗,能有效缓解症状,于其病情转归有利。
[Abstract]:Objective: to investigate the clinical value of triamcinolone acetonide point injection combined with traditional Chinese medicine Shenkang lotion in the treatment of anus eczema. Methods: 124 patients with anus eczema and eczema syndrome from March 2013 to December 2015 were randomly divided into study group and control group. There were 5 effective cases in the control group and 6 cases in the study group. Control group: warm water site-bath brucinic acid momethasone cream external coating scheme. Study group: triamcinolone acetonide acupoint injection combined with external washing of traditional Chinese medicine skin-Kang lotion. The clinical efficacy and incidence of adverse reactions were compared between the two groups. The relative indexes [serum interleukin-2, interleukin-4 (IL-4), interleukin-6 (IL-6) and gastrin gas) were recorded before and after treatment. The maximum diameter of skin lesions and symptoms (pruritus) were recorded. Scorching, pain, large constipation, short urination, dry mouth upset) score changes. Results: the total effective rate of treatment in the study group was significantly higher than that in the control group (91.1 vs 72.4). After 2 weeks of treatment, the serum IL-2 level in both groups was significantly higher than that before treatment, and in the study group, the level of some indexes (serum IL-4, IL-6 gas), the maximum diameter of skin lesion and the evaluation of symptom score were significantly lower than those before treatment. In the control group, the difference was statistically significant (P 0.05). There were 1 case of menstrual disorder, 1 case of dizziness and 1 case of nausea after treatment in the study group and 1 case of local burning sensation in the control group. There was no significant difference in the incidence of adverse reactions between the two groups (P 0.05). Conclusion: the treatment of anus eczema with triamcinolone acetonide acupoint injection combined with traditional Chinese medicine skin lotion can effectively relieve the symptoms and is beneficial to the outcome of the disease.
【作者单位】：苏州市立医院北区皮肤性病科;
【分类号】：R758.23

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