鳞状细胞癌抗原在各种皮肤疾病中的表达及影响因素

发布时间：2018-06-21 08:32

本文选题：SCCA + 湿疹　；参考：《浙江大学》2010年硕士论文

【摘要】： 目的：探讨鳞状细胞癌抗原(Squamous cell carcinoma antigen,SCCA)在各种皮肤疾病中的表达水平及其影响因素。方法：回顾性分析2008.1-2010.4出院患者SCCA值。按疾病分组及治疗前后SCCA值统计分析,对湿疹银屑病的患者按年龄、性别、受累面积、分型分期等统计分析,红皮病进行描述分析。结果：湿疹、银屑病、红皮病、大疱性疾病与对照组相比血清SCCA值明显升高,其中位数分别为：4.4ng/ml、13.3ng/ml、46.6ng/ml、3.1ng/ml,与对照组有非常显著的统计学差异(P0.01),感染性皮肤疾病、结缔组织疾病、血管炎,其中位数分别为：0.6ng/ml、0.4ng/ml、0.6ng/ml,与对照组无明显的统计学差异(P0.05)；治疗后SCCA值较治疗前下降明显,治疗前、后Ln(SCCA值)分别为：3.03±1.25、1.50±1.23,两者有非常显著的统计学差异(P0.01)；湿疹：年龄
[Abstract]:Objective: to investigate the expression level of squamous cell carcinoma antigen (squamous cell carcinoma antigenia) in various skin diseases and its influencing factors. Methods: the SCCA values of patients discharged from hospital in 2008.1-2010.4 were analyzed retrospectively. The patients with psoriasis of eczema were analyzed according to age, sex, area of involvement, type and stage, and erythroderma according to the SCCA value before and after treatment. Results: the levels of serum SCCA in eczema, psoriasis, erythroderma, bullous disease were significantly higher than those in control group, and the median values of SCCA were 13.3 ng / ml, 46.6ng / ml, 3.1ng / ml, respectively, compared with the control group. There was a very significant statistical difference between the two groups (P 0.01), infectious skin disease, connective tissue disease, and connective tissue disease. In vasculitis, the median values were 0. 6 ng / ml, 0. 4 ng / ml and 0. 6 ng / ml, respectively. There was no significant difference between the two groups (P0. 05; SCCA value after treatment was significantly lower than that before and after treatment) was 3. 03 卤1. 251.50 卤1. 23, there was a very significant statistical difference between the two groups (P 0. 01);
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R758.6

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