CT引导胸椎旁背根神经节损毁术治疗带状疱疹后神经痛70例评价

发布时间：2018-06-21 23:41

本文选题：神经节 + 脊髓　；参考：《中国疼痛医学杂志》2014年02期

【摘要】：目的:评价CT三维重建引导下经胸椎旁行背根节阿霉素损毁术对胸背部带状疱疹后神经痛患者的疗效。方法:胸背部带状疱疹后神经痛患者70例,在CT三维重建引导下经胸椎旁穿刺近背根节注射0.3%阿霉素10 mg。分别于术前、术后当日、7 d、1个月、3个月进行VAS评分并评价疼痛缓解程度,计算有效率和复发率,观察并发症的发生情况。结果:治疗后当日、7 d、1个月、3个月VAS评分与术前比较均降低(P0.01),治疗后当日、7 d、1个月、3个月有效率分别为82%、80%、85%、76%。治疗后1、3个月复发率为9%、13%。局部肿胀、血肿的发生率12%,神经支配区麻木发生率17%,对症治疗后恢复;未见气胸、神经损伤、脊髓损伤严重等并发症。结论:CT引导下经胸椎旁背根节阿霉素损毁术治疗PHN疗效确切,且安全性良好。
[Abstract]:Objective: to evaluate the effect of CT three-dimensional reconstruction guided by adriamycin lesion on dorsal root ganglion in patients with postherpetic neuralgia. Methods: seventy patients with postherpetic neuralgia were injected with 0.3% adriamycin 10 mg through paraspinal proximal dorsal root ganglion under the guidance of three-dimensional CT reconstruction. VAS scores were performed before operation, 7 days, 1 month and 3 months after operation, and the degree of pain relief was evaluated, the effective rate and recurrence rate were calculated, and the occurrence of complications was observed. Results: the VAS scores were significantly lower at 7 days, 1 month and 3 months after treatment than before treatment (P0.01). The effective rates of VAS on 7 days, 1 month and 3 months after treatment were 82 and 8576, respectively. The recurrence rate 1 and 3 months after treatment was 9 and 13. The incidence of local swelling, hematoma and nerve innervation were 12 and 17, respectively. There were no complications such as pneumothorax, nerve injury, spinal cord injury and so on. Conclusion the treatment of PHN with adriamycin lesion through thoracic paraspinal dorsal root ganglion guided by 10% CT is effective and safe.
【作者单位】：天津医科大学第二医院疼痛治疗中心;天津市麻醉学研究所天津医科大学总医院麻醉科;
【基金】：天津市自然科学基金(09JCYBJC13200) 天津医科大学第二医院科研基金项目(Y1205)
【分类号】：R752.12

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