孕妇生殖道支原体属感染的调查与药敏分析

发布时间：2018-07-01 13:37

本文选题：支原体属 + 感染　；参考：《中华医院感染学杂志》2014年03期

【摘要】：目的了解医院性病门诊和产科门诊孕妇生殖道支原体属感染现状和药物敏感性,分析支原体属耐药性的变化趋势,为临床科学诊断和治疗提供参考依据。方法回顾性分析2011年10月-2012年10月2 186例孕妇支原体属鉴定及12种药物敏感性试验的结果。结果 2 186例孕妇中支原体属培养阳性292例,阳性率为13.36%,其中解脲脲支原体(Uu)感染206例,感染率为9.42%,人支原体(Mh)感染73例,感染率为3.34%,Uu+Mh感染13例,感染率为0.59%;Uu对米诺环素、多西环素、交沙霉素的敏感性最高,分别为99.54%、98.10%、97.70%,对司帕沙星、红霉素、左氧氟沙星的耐药率最高,分别为59.82%、55.25%、47.95%;Mh对米诺环素、多西环素、交沙霉素的敏感性最高,分别为98.84%、97.67%、97.67%,对红霉素、诺氟沙星均100.00%耐药。结论孕妇生殖道中广泛存在支原体属感染,生殖道支原体属对常用抗菌药物的耐药性已相当严重,应引起临床重视。
[Abstract]:Objective to investigate the present situation and drug sensitivity of mycoplasma in genital tract of pregnant women in STD and obstetrical outpatient clinics in hospitals, and to analyze the trend of drug resistance of Mycoplasma in order to provide reference for clinical diagnosis and treatment. Methods A retrospective analysis was made on the identification of mycoplasma from October 2011 to October 2012 in 2 186 pregnant women and the results of 12 drug sensitivity tests. Results among the 2 186 pregnant women, 292 cases were positive for mycoplasma, the positive rate was 13.3636. Among them, 206 cases were Ureaplasma Urealyticum (UU) infection, the infection rate was 9.42%, and 73 cases were mycoplasma hominis (Mh) infection, the infection rate was 3.3434 UU Mh infection in 13 cases, the infection rate was 0.59 UU vs minocycline. The sensitivity of doxycycline and josamycin was the highest, which were 99.54 and 98.10100.97.70, respectively. The resistance rates of sparfloxacin, erythromycin and levofloxacin to sparfloxacin, erythromycin and levofloxacin were the highest, which were 59.82 and 55.255.95Mh, respectively. The sensitivity of doxycycline, doxycycline and josamycin to minocycline, doxycycline and josamycin was the highest, and the sensitivity to erythromycin, to doxycycline and josamycin was the highest, respectively. The drug resistance of norfloxacin was 100.00%. Conclusion Mycoplasma infection is widespread in the reproductive tract of pregnant women. The drug resistance of Mycoplasma in reproductive tract to common antimicrobial agents is quite serious, which should be paid more attention to in clinic.
【作者单位】：复旦大学附属金山医院皮肤科;
【基金】：上海市金山区卫生局基金资助项目(2011-09)
【分类号】：R446.5;R759

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